La cinética de la esterificación de ácidos carboxílocos es de segundo orden con repecto al alcohol

Resumen

Esterification of carboxylic acids with alcohols is considered as A_AC2 type reaction. The specific rate of esterification of acetic acid with methanol, in mixtures of acetonitrile-methanol showed a quadratic dependence on the alcohol concentration. This second order dependence suggests a general base catalyzed mechanism analogous to the [H₂O]² kinetic dependence observed in the acidcatalyzed hydrolysis of carboxylic esters, in highly aqueous media.