Población y Salud en Mesoamérica ISSN electrónico: 1659-0201

OAI: https://revistas.ucr.ac.cr/index.php/psm/oai
Factors associated to mortality in Mexican population with AIDS in contrast to others human population. Systematic review and meta-analysis
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Latin America

How to Cite

Pertuz-Belloso, S. B. (2016). Factors associated to mortality in Mexican population with AIDS in contrast to others human population. Systematic review and meta-analysis. Población Y Salud En Mesoamérica, 13(2). https://doi.org/10.15517/psm.v13i2.22162


The objective of this work is to determinate factors that could be associated to AIDS patient’s mortality in a meta-analytic study from 2010-2014 in which it was reviewed information about AIDS and the mortality causes in NCBI data base. Data, embed into a matrix, were processed statistically processed according to meta-analysis standards in OpenEpi program (3.0.3). Results show that secondary diseases, such as tuberculosis (rate: 0.1), toxoplasmosis (rate: 1), and Kaposi Sarcoma (rate: 1) keep having an important place among the mortality factors of global AIDS population. Nerveless, data also show that the growing antiretroviral resistance is the main AIDS population’s problem (rate: 10.0). The polymorphism of the immunological receptors on the mortality of AIDS populations (rate: 0.01) has a low impact. In Mexico, this population’s mortality rate is high (rate: 4.5) and very similar to other Latin-American countries (rate: 3.5). Among the determiners of these mortality rates in Mexican AIDS population there could be found low immunological recovery and bad response to antiretroviral therapy.
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Las referencias marcadas con un asterisco indican estudios comprendidos en el meta-análisis.

*Avilés-Salas, A., Cornejo-Juárez, P., y Sobrevilla-Calvo, P. de J. (2011). Coexistencia de linfoma plasmablástico, sarcoma Kaposi y enfermedad de Castleman en un paciente con infección por el virus de inmunodeficiencia humana. Rev Chil Infect, 28, 76-80. doi: 10.4067/S0716-10182011000100015

*Basavaprabhu, A., Soundarya, M., Deepak, M., y Satish, R. (2012). CNS Toxoplasmosis Presenting with Obstructive Hydrocephalus in Patients of Retroviral Disease-A Case Series. Med J Malaysia, 67, 214-216.

*Carganico, A., Dupke, S., Ehret, R., Berg, T., Baumgarten, A., Obermeier, M., y Walter, H. (2014). New dolutegravir resistance pattern identified in a patient failing therapy. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19749

*Castilho, J. L., Luz, P. M., Shepherd, B. E., Turner, M., Ribeiro, S. R., y Bebawy, S. S. (2015). HIV and cancer: a comparative retrospective study of Brazilian and U.S. clinical cohorts. Infectious Agents and Cancer, 10, 1-10.

Chatterjee, A., Rathore, A., Viddyant, S., Kakkar, K., y Dhole, T.N. (2012). Chemokines and chemokines receptors in susceptibility to HIV-1 infection and progression to AIDS. Disease Markers, 32, 143-151.

*Corrêa, V. V., Martínez, B. M. F., Mendoza-Sassi, R. A., Silveira, J. M., Soares, M. A., y Barral De Martínez, A. M. (2011). The effect of combined polymorphisms in chemokines and chemokine receptors on the clinical course of HIV-1 infection in a Brazilian population. Mem Inst Oswaldo Cruz, Rio de Janeiro, 106, 408-414.

*Cortes, C. P., Wehbe, F. H., McGowan, C. C., Shepherd, B. E., Duda, S. N., Jenkins, C. A., … Sterling, T. R. (2013). Therapy Initiation: Association with Mortality in HIV-Related Tuberculosis. Plos One, 8. doi:10.1371/journal.pone.0074057

Dean, A.G., Sullivan, K.M., y Soe, M.M. (2015). OpenEpi: Open Source Epidemiologic Statistics for Public Health [Software]. Recuperado de www.OpenEpi.com

*Del Amo, J., Jarrin, I., May, M., Dabis, F., Crane, H., Podzamczer, D., … Gill, M. J. (2013). Influence of geographical origin and ethnicity on mortality in patients on therapy in Canada, Europe, and the United States. Clin Infect Dis, 56, 1810-1811.

Dennis, A. M., Napravnik, S., Seña, A. C., y Eron, J. J. (2011). Late Entry to HIV care among Latinos compared with no-Latinos in a Southeastern US cohort. CID, 53, 480-487.

*Fernandes, L. S. (2012). Human immunodeficiency virus and cancer. A population of HIV-infected patients at Hospital de Santa Maria and predictors of cancer. GERMS, 2(2), 60-75.

*Gheuens, S., Cheeseman, S. H., y Koralnik, I. J. (2011). Hidden in plain view: emergence of Progressive Multifocal Leukoencephalopathy after treatment of CNS Toxoplasmosis. Acta Neurol Belg, 111, 217–219.

*González, M. A., Martin, L., Muñoz, S., y Jacobson, J. O. (2011). Patterns, trends and sex differences in HIV/AIDS reported mortality in Latin American countries: 1996-2007. BMC Public Health, 11, 605. doi: 10.1186/1471-2458-11-605.

*Gopal, S., Achenbach, C. J., Yanik, E. L., Dittmer, D. P., Eron, J. J., y Engels, E.A. (2014). Moving Forward in HIV-Associated Cancer. J Clin Oncology, 32, 876-880.

*Herman, S. M., van Leth, F., Kiragga, A. N., Hoepelman, A. I. M., Lange, J. M. A., y Manabe, Y. C. (2012). Unrecognized tuberculosis at therapy initiation is associated with lower CD4+ T cell recovery. Trop Med Int Health, 17, 1527-1533.

*Hirai, Y., Yoshihara, T., Motoji, T., y Totsuka, K. (2012). Facial-oropharyngeal Kaposi Sarcoma in a HIV-seropositive man. Intern Med, 51, 2989-2990. doi:10.2169/internalmedicine.51.8620

Instituto Nacional de Estadística y Geografía de México. (2011). Tasa de Mortalidad por VIH/SIDA por 100 mil habitantes del 2009-2011. Recuperado de http://www3.inegi.org.mx/sistemas/biinegi/?ind=6300000058

Kamat, A., Misra, V., Cassol, E., Ancuta, P., Yan, Z., Li, C., Morgello, S., y Gabuzda, D. (2012). A plasma biomarker signature of immune activation in HIV patients on therapy. Plos One, 7. doi:10.1371/journal.pone.0030881

*Khabour, O. F., Abu-Haweleh, L. J., y Alzoubi, K. H. (2013). Distribution Of CCR-5D32, CCR2-64I, and SDF-1-3: A Alleles Among Jordanians. AIDS Research And Human Retroviruses, 29, 151-155.

*Kouri, V., Alemán, Y., Peréz, L., Peréz, J., Fonseca, C., Correa, C., … Laethem, K. (2014). High frequency of antiviral drug resistance and non-b subtypes in HIV-1 patients failing antiviral therapy in Cuba. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19754

*Kouri, V., Martínez, P. A., Capò, V., Blanco, O., Rodríguez, M. E., Jiménez, N., … Hengge, U. (2012). Kaposi’s Sarcoma and Human Herpesvirus8 in Cuba: Evidence of subtype B expansion. Virology, 432, 361–369.

*Lejeune, M. A., Mirô, J. M., Lazzari, E. D., García, F., Claramonte, X., Martínez, E., … Gallart, T. (2011). Restoration of T Cell Responses to Toxoplasma gondii after Successful Combined Therapy in Patients with AIDS with Previous Toxoplasmic Encephalitis. CID, 52, 662-670.

Liovat, A. S., Rey-Cuillè, M. A., Lecuroux, C., Jacquelin, B., Girault, I., Petitjean, G., … Müller-Trutwin, M. (2012). Acute plasma biomarkers of T cell activation set-point levels and of disease progression in HIV infection. Plos One, 7. doi:10.1371/journal.pone.0046143

*Liu, W. C., Chang, L. H., Wu, P. Y., Luo, Y. Z., Wu, C. H., Su, Y. C., … Hung, C. C. (2014). Seroincidence of HIV and prevalence of transmitted drug resistance of HIV-1 strains among persons seeking voluntary counselling and testing in Taiwan. Journal of the International AIDS Society, 17(Suppl 3).

*Luu, H. N., Amirian, E. S., Chiao, E. Y., y Scheurer, M. E. (2014). Age patterns of Kaposi’s sarcoma incidence in a cohort of HIV-infected men. Cancer Med, 3, 1635–1643.

*Machala, L., Maly, M., Beran, O., Jilich, D., y Kodym, P. (2013). Incidence and clinical and immunological characteristics of primary Toxoplasma gondii infection in HIV-infected patients. Int J Infect Diseases, 17, e892–e896. doi:10.1016/j.ijid.2013.03.017

Mahajan, S., Agosto-Mojica, A., Aakinkeel, R., Raynolds, J.L., Nair, B.B., Sykes, D.E., … Schwartz, S.A. (2010). Role of chemokines and cytokine polymorphisms in the progression of HIV-1 disease. Biochem Biophys Res Commun, 396, 348-352.

*Marcelin, A.G., Charpentier, C., Wirden, M., Descamps, D., y Calvez, V. (2014). Less frequent follow-up in routine care than in trials does not impact resistance selection in patients failing DRV/r or ATV/r first line treatment. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19744

*McFaul, K., Lim, C., Jones, R., Asboe, D., Pozniak, A., Sonecha, S., Boffito, M., y Nwokolo, N. (2014). Transmitted drug resistance in treatment naive HIV-infected persons in London in 2011 to 2013. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19747.

MedCalc Software. (2015). MedCalc [Software]. Recuperado de https://www.medcalc.org/download.php

Mederos, C. L. M., Reyes, P. A., Valdés, A. L., Rodríguez, D. F., Sardiñas, A. M., Martínez, M. R., y Díaz Romero, R. (2014). Confección por Mycobacterium malmoense y Mycobacterium tuberculosis en paciente con el síndrome de inmunodeficiencia humana. Rev Perú Med Exp Salud Pública, 31, 788-792.

Mosier, D. E. (2009). How HIV changes it`s tropism: evolution and adaptation?. Curr Opin HIV AIDS, 4, 125-130.

*Nelson, B., Borok, M. Z., Mhlanga, T. O., Makadzange, A.T., y Campbell, T. B. (2013). AIDS-associated Kaposi sarcoma: outcomes after initiation of therapy at a university-affiliated hospital in urban Zimbabwe. Int J Infect Diseases, 17, e902–e906. doi:10.1016/j.ijid.2013.04.011

Nissapartorn, V., Lee, C., Fatt, K., Loon, L.C., Mahmud, R., y Abdullah, A. (2014). Toxoplasmosis in HIV/AIDS patients: A current situation. Jnp J. Infect Dis, 57, 160-165.

*Ogoina, D., Adekunle, V., Obiako, R., Umar, A., Akolawole, M., y Ovosi, J. (2011). Disseminated infections due to Immune Reconstitution Inflammatory Syndrome after Highly Active Therapy - Report of 3 cases from Nigeria. Pan African Med J, 9, 1-5.

*Osunkalu, V. O., Akanmu, S. A., Ofomah, N. J., Onyiaorah, I. V., Adediran, A., y Akinde, R.O. (2011). Seroprevalence of Toxoplasma gondii IgG antibody in HIV-infected patients at the Lagos University Teaching Hospital. HIV/AIDS - Research and Palliative Care, 3, 101–105.

*Parczewski, M., Witak-Jedra, M., Maciejewska, K., Bociaga-Jasik, M., Skwara, P., Garlicki, A., … Leszczyszyn-Pynka M. (2014).Time trends in HIV-1 transmitted drug resistance mutation frequency in Poland. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19753

Pimpin, L. N., Drumright, M. E., Kruijshaar. I., Abubakar, B., Rice, V., Delpech, V., … Ködmön, C. (2011). Tuberculosis and HIV co-infection in European Union and European Economic Area countries. Eur Respir J, 38, 1382–1392.

*Pittore, B., Loris-Pelagatti, C., Deiana, F., Ortu, F., Maricosu, E., Cossu, S., y Sotgiu, G. (2015). Isolated Kaposi Sarcoma of the Tonsil: A Case Report and Review of the Scientific Literature. Case Reports in Otolaryngology, 2015. doi:10.1155/2015/874548

*Rocha-Pereira, N., Duro, R., Piñero, C., Figueiredo, C., Sofia-Santos, A., Soares, J., Serrão, R., y Sarmento, A. (2014). Primary drug resistance at diagnosis of HIV-1 infection: a Portuguese cohort. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19761

Rodríguez, C., Martínez, E., Bolívar, G., Sánchez, S., y Carrascal, E. (2013). Toxoplasmosis of the spinal cord in an immunocompromised patient: case report and review of the literature. Colombia Médica, 44, 232-235.

*Saldarriaga-Cantilloa, A., Bravoa, L. E., Londoño, O., García, L. S., y Collazosa, P. (2012). Epidemiological surveillance of the HIV/AIDS complex through the analysis of trends in the incidence of Kaposi’s sarcoma in Cali, Colombia. Colombia Médica, 43, 273-280.

*Sayan, M., Sargyn, F., Inan, D., Yyldyz-Sevgi, D., Kocagul, C.A., Cagatay, A., … Willke, A. (2014). Transmitted drug resistance mutations in newly diagnosed HIV-1 positive patients in Turkey. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19750

Stepchenkova, T., Martynenko, O., y Yurchenko, O. (2014). Analysis of causes of death among HIV-infected patients of Kiev Regional AIDS Center during 2013. Journal of the International AIDS Society, 17(Suppl 3), 19617. doi:10.7448/IAS.17.4.19617

*Sukthana, Y., Mahittikorn, A., Wickert, H., y Tansuphaswasdikul, S. (2012). A promising diagnostic tool for toxoplasmic encephalitis: tachyzoite/bradyzoitenstage-specific RT-PCR. Int J Infect Diseases, 16, e279–e284. doi:10.1016/j.ijid.2011.12.009

*Tanon, A., Jaquet, A., Ekouevi, D. K., Akakpo, J., Adoubi, I., y Diomande, I. (2012). The Spectrum of Cancers in West Africa: Associations with Human Immunodeficiency Virus. PLoS ONE, 7. doi:10.1371/journal.pone.0048108

*Thariat, J., Kirova, Y., Sio, T., Choussy, O., Vees, H., Schick, U., … Miller, R. C. (2012). Mucosal Kaposi sarcoma, a Rare Cancer Network study. Rare Tumors, 4, e49. doi:10.4081/rt.2012.e49

*Unemori, P., Leslie, K. S., Hunt, P. W., Sinclair, E., Epling, L., Mitsuyasu, R., … Maurer, T. A. (2013). Immunosenescence is associated with presence of Kaposi's sarcoma in treated HIV infection. AIDS, 27, 1735–42. doi:10.1097/QAD.0b013e3283601144

*von Braun, A., Braun, D. L., Kamarachev, J., Günthard, H. F. (2014). New Onset of Kaposi Sarcoma in a Human Immunodeficiency Virus-1-Infected Homosexual Man, Despite Early Treatment, Sustained Viral Suppression, and Immune Restoration. Open Forum Infectious Diseases, 1. doi:10.1093/ofid/ofu005

*Xavier, A. G., González-Cademartori, B., Azevedo-Da Cunha-Filho, N., y Da Rosa-Farias, N. A. (2013). Evaluation of seroepidemiological toxoplasmosis in hiv / aids patients in the south of Brazil. Rev. Inst. Med. Trop. Sao Paulo, 55, 25-30.

*Xiao, J., Gao, G., Li, Y., Zhang, W., Tian, Y., Huang, Y., Zhao, H. (2013). Spectrums of Opportunistic Infections and Malignancies in HIV-Infected Patients in Tertiary Care Hospital, China. PLoS ONE, 8. doi:10.1371/journal.pone.0075915

Yohanes, T., Debalke, S., y Zemene, E. (2014). Latent Toxoplasma gondii Infection and Associated Risk Factors among HIV-Infected Individuals at Arba Minch Hospital, South Ethiopia. AIDS Research and Treatment, 2014. doi:10.1155/2014/652941

*Zoufaly, A., Jochum, J., Hammer, R., Nassimi, N., Raymond, Y., y Burchard, G. D. (2014). Determinants of HIV-1 drug resistance in treatment-naıve patients and its clinical implications in a treatment program in Cameroon. Journal of the International AIDS Society, 17(Suppl 3). doi:10.7448/IAS.17.4.19615



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