Protective Effect of Quinoa Extract on Periodontium and Serum YKL-40 Levels of Albino Rat Depression Model

M. Abd-elmonsif, Nehad; Gamal, Sherif; El Deeb, Mona

doi:10.15517/6vyxfq08

Authors

Nehad M. Abd-elmonsif Department of Oral Biology, Faculty of Oral and Dental Medicine, Future University in Egypt, Cairo, Egypt. Author https://orcid.org/0000-0003-0576-5099
Sherif Gamal Research Labs Supervisor, Faculty of Pharmacy, Future University in Egypt, Cairo, Egypt. Author https://orcid.org/0000-0002-5266-8403
Mona El Deeb Department of Oral Biology, Faculty of Oral and Dental Medicine, Future University in Egypt, Cairo, Egypt. Author https://orcid.org/0000-0002-1339-4446

DOI:

https://doi.org/10.15517/6vyxfq08

Keywords:

Depression; Periodontium; YKL-40; Quinoa extract.

Abstract

The research was done to explore the influence of quinoa extract on periodontium, and to assess serum YKL-40 level in a depression rat model. An overall number of 30 male albino rats weighing170-180 g were used. Animals were grouped into three categories; group I: control group, group II: depressed group, group III: depressed group treated with 600 mg/kg body weight quinoa extract. The experimental duration extended to a period of 21 days. Blood samples obtained from the heart were transported to biochemistry tubes for ELISA analysis following euthanization. Mandibular molar region specimens were subjected to decalcification for histological evaluation. Quinoa extract ameliorated the degenerative changes of periodontium in the experimental depression model, increased body weight and serum serotonin level, and decreased serum cortisol and YKL-40 levels. Quinoa extract may be utilized as a preventative measure against the periodontal damage brought on by depression.

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