Odovtos - International Journal of Dental Sciences
type: channel
description: Odovtos – International Journal of Dental Sciences (Odovtos-Int J Dent Sc) is the official scientific publication of the Faculty of Dentistry, University of Costa Rica. The main objective of this peer-reviewed journal is to disseminate original and transcendental knowledge in the field of dentistry and its specialties. Odovtos-Int J Dent Sc primary readership consists of dentists, dental educators, academics, dental students, researchers, health professionals and general public interested in expanding their knowledge in the area. Our journal consider unpublished and original manuscripts in ENGLISH with a prominent focus on critical and innovative data, promoting major clinical, academic and scientific research, based on International Committee of Medical Journal Editors (ICMJE) recommendations. Odovtos - Int J Dent Sc offers Online-First publication, allowing frequent dissemination of its content. You can access our Journal Normalized Citation Impact and Citation Impact in InCites-Clarivate: Incites - Clarivate Citation Impact 2023 JCR Impact Factor list of Clarivate Analytics: 0.6. Qualis 3 SCOPUS WHY SUBMIT YOUR PAPER TO OUR JOURNAL? Odovtos – International Journal of Dental Sciences compromises to disseminate their contents worldwide, through collaborations with several Dental Schools, online databases, index and repositories, website, social media, among others. All submitted manuscripts are peer-reviewed based solely on the criteria of quality, innovation and pertinence. The pre-publication process is brief due to online submission. Moreover, Odovtos-Int. J. Dent. Sc. is an Online-First Journal, which allows frequent publication in Internet according to Open Access Initiative, favoring the diffusion of its content. Journal indexed: ODOVTOS is indexed in Clarivate Analytics with a 2023 JCR Impact Factor list of Clarivate Analytics: 0.6. <a href="https://www.scimagojr.com/journalsearch.php?q=21101088429&tip=sid&clean=0#:~:text=%3Ca%20href%3D%22https%3A//www.scima…
publisher: Universidad de Costa Rica
language: en
publication name: Odovtos - International Journal of Dental Sciences
issn: 1659-1046
copyright: ODOVTOS - Int. J. Dent. Sc. endorses CC BY-NC-SA This license enables reusers to distribute, remix, adapt, and build upon the material in any medium or format for noncommercial purposes only, and only so long as attribution is given to the creator. If you remix, adapt, or build upon the material, you must license the modified material under identical terms. CC BY-NC-SA includes the following elements: BY: credit must be given to the creator. NC: Only noncommercial uses of the work are permitted. SA: Adaptations must be shared under the same terms.
items: Microtensile bond strength of resin cements to 3-D printed and milled temporary restorative resins
items: Uses of Chitosan-Based Hydrogels in Dentistry: A Systematic Review
items: The use of thyroid shielding and lead apron in dentistry. Position Statement from the Costa Rican Academy of Oral and Maxillofacial Radiology
items: Genetic Analysis of TPM1 Gene Polymorphism (rs11071720) in Patients with Non-Syndromic Cleft Lip/Palate in the South Indian Population. A Case Control Study
items: Intraoral and Extraoral Scanning Technologies in the Digital Workflow Era: An Integrative Review with Artificial Intelligence
items: Effect of the COVID-19 Pandemic on the Educational Indicators in the Dentistry Career of the University of Costa Rica
items: Factors Associated with the Perception of Prehospital Internship Training of Dental and Other Health Sciences Students in the COVID-19 Context
items: Immunohistochemical and Clinicopathologic Correlation of DNA Methyltransferase 3A and (C-X-C motif) Ligand 1 in Oral Squamous Cell Carcinoma
items: Immunoexpression of ALDH1A1, FGFR2, CD44 and Caspase-3 in Oral Squamous Cell Carcinoma and Leukoplakia: A Pilot Study
items: Open Access and Bibliometric Data: Odovtos-Int.J.Dent.Sc.
items: CBCT Study of Root Apices Distance to Mandibular Canal in Peruvian Population
items: Immunological and Bacteriological Monitoring of Periodontal Tissue in Pregnancy
items: Assessment of Electromyography in Evaluating Masseter Muscle Activity in Oral Submucous Fibrosis with Different Treatment Modalities: a Systematic Review
items: 3D Printing Characteristics and Mechanical Properties of a Bio Scaffold Obtained from a Micro-CT Scan, Using the Fused Deposition Modeling Technique
items: Effects of Whitening Dentifrices on the Enamel Color, Surface Roughness, and Morphology
items: Effect of Dental Distance from Implant and MAR Algorithm on the Detection of Vertical Root Fracture in CBCT Images
items: The Effect of Whitening Toothpastes on Colour Change and Surface Roughness of Restorative Materials
items: Elimination of E. faecalis and C. albicans Biofilm: A Comparison Between Single and Multiple File Systems in an Ex Vivo Study
items: Effect of Different Obturation Techniques on Sealer Penetration into Dentinal Tubules after Final Irrigation with XP-Endo Finisher File
items: Autophagic-Related Anticancer Effect of Grapes Extract and Tomatoes Extract: Ex-Vivo Study
items: Effect of Voxel Size of Micro-CT on the Assessment of Root Canal Preparation
items: Methylation Analysis of Rb, P16, MGMT, and hMLH-1in Mucoepidermoid Carcinomas. A Pilot Study
items: CD44+ Cells Influence Oral Squamous Cell Carcinomas in Two Comparative Age Groups
items: Chronic Bi-Maxillary Osteomyelitis Caused by Actinomycetes in a Patient with Severe COVID-19
items: Effect of Energy Level of Photobiomodulation Therapy on Bone Repair in Rats
items: Dental Age Estimation by Assessing the Pulp Volume of Five Teeth in a Peruvian Population Using Cone Beam Computed Tomography Images
items: Impact of Oral Conditions on Quality of Life in Peruvian Preschoolers in Rural and Urban Areas
items: The Association Between Sleep Quality, Fatigue and Periodontal Status: a Pilot Study
items: Terminal Efficiency, Lag and Dropout in Cohorts from 2007 to 2014 of Dental Students at the University of Costa Rica
items: Antimicrobial Efficacy of the Use of Mouthwash with Cetylpiridinium Chloride for Aerosol Producing Procedures. A Systematic Review

Microtensile bond strength of resin cements to 3-D printed and milled temporary restorative resins
type: item
description: To evaluate the microtensile bond strength (µTBS) of two resin cements to 3D printed and milled CAD/CAM resins used for provisional fixed partial dentures. Blocks (5 x 5 x 5 mm) of three 3D-printed resins (Cosmos3DTemp / Yller; Resilab3D Temp / Wilcos and SmartPrint BioTemp, / MMTech) were printed (Photon, Anycubic Technology Co.). A milled material (VitaCAD-Temp, VITA) was used as control. Half the specimens were sandblasted and the rest were untreated. Two blocks were bonded with the corresponding resin cement: PanaviaV5 (Kuraray Noritake) and RelyX Ultimate (3M Oral Care). After 24 hours, the bonded blocks were sectioned into 1 x 1 mm side sticks. Half the beams were tested for µTBS and the other half was thermocycled (5000 cycles, 30s dwell-time, 5s transfer time) before µTBS testing. A four way Generalized Linear Model (material*sandblasting*cement*aging) analysis was applied. VITA exhibited the lowest µTBS, regardless of the cement, sandblasting and thermocycling. Sandblasting significantly improved the µTBS of VIT, especially after aging, but did not improve the µTBS of 3D printed resins. Sandblasting was not beneficial for 3D printed resins, although is crucial for adhesive cementation of milled temporary resins. Airborne particle abrasion affects the integrity of 3D-printed resins, without producing a benefit on the microtensile bond strength of these materials. However, sandblasting is crucial to achieve a high bond strength on milled temporary resins.
subject: Original Basic Research Articles
  topic: section
subject: Computer-aided design; Computer-aided manufacturing; 3D printing; Provisional restoration; Bond strength.
  topic: keywords
creator: Jorge Soto-Montero
creator: Beatriz de Cassia Romano
creator: Mayara dos Santos Noronha
creator: Carolina Bosso André
creator: Marcelo Giannini
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 82
ending page: 98
doi: 10.15517/ijds.2023.55808

Uses of Chitosan-Based Hydrogels in Dentistry: A Systematic Review
type: item
description: The objective of this article was to carry out a systematic review of the literature to determine the different therapeutic uses of chitosan-based hydrogels and their uses in dental therapy, as well as the modification and improvement of dental materials to promote research related to chitosan and its incorporation into dentistry as an adjunct or replacement in some dental treatments. Chitosan is a natural polymer obtained from the deacetylation of chitin, a polysaccharide abundant in nature, which, due to its biocompatibility, high biodegradability, non-antigenicity, and its ease of acquisition, has attracted biomedical interest, including in dentistry. Recent studies have shown that chitosan can be integrated into dental materials to obtain remineralizing effects, such as for antimicrobial agents, osteogenic agents, and pulp regeneration treatment. A bibliographic search was carried out in PubMed from 2018 to 2023. The results showed a wide range of uses for chitosan in the dental field, particularly its use as a remineralizing agent for tooth enamel; It has also been used in tissue regeneration mainly because of its osteogenic activity, as an antimicrobial agent, and as a vehicle for the application of medications. The use of chitosan as a nanobiomaterial is an interesting topic, since chitosan shows potential for new dental materials, either as an active ingredient or as an adjuvant vehicle for other materials.
subject: Literature Review Articles
  topic: section
subject: Hydrogel; Chitosan; Xylitol; Remineralization, Tooth enamel.
  topic: keywords
creator: Jesús Antonio Valenciana-Solís
creator: César Gaitán-Fonseca
creator: Luis Alejandro Aguilera-Galavíz
creator: Gabriel Alejandro Martínez-Castañón
creator: Verónica Zavala-Alonso
creator: Carlos Bermúdez-Jiménez
rights: Copyright (c) 2024 Jesús Antonio Valenciana-Solís, César Gaitán-Fonseca, Luis Alejandro Aguilera-Galavíz, Gabriel Alejandro Martínez-Castañón, Verónica Zavala-Alonso, Carlos Bermúdez-Jiménez https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-27
publication date: 2026-04-27
starting page: 99
ending page: 112
doi: 10.15517/ijds.2024.60340

The use of thyroid shielding and lead apron in dentistry. Position Statement from the Costa Rican Academy of Oral and Maxillofacial Radiology
type: item
description: .
subject: Letters to the Editor
  topic: section
creator: Deivi Cascante-Sequeira
creator: Lucía Barba Ramírez
creator: Ana Cecilia Ruiz-Imbert
rights: Copyright (c) 2024 Deivi Cascante-Sequeira, Lucía Barba Ramírez, Ana Cecilia Ruiz-Imbert https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-27
publication date: 2026-04-27
starting page: 10
ending page: 19
doi: 10.15517/ijds.2024.60558

Genetic Analysis of TPM1 Gene Polymorphism (rs11071720) in Patients with Non-Syndromic Cleft Lip/Palate in the South Indian Population. A Case Control Study
type: item
description: The aim of this study was to find out if there was an association between TPM1 gene polymorphism (rs11071720) and non-syndromic cleft lip and palate in humans. Twenty five patients with non-syndromic cleft lip and palate (NSCL/P) and twenty five healthy patients as controls were enrolled in the study. Whole blood drawn from the participants was used to obtain genomic DNA. Sequence specific primers were used to amplify the region spanning the polymorphic site of the TPM1 gene using polymerase chain reaction (PCR). The genotype of the subjects was identified employing the RFLP technique. The genotype and allele frequency distributions in the non-syndromic cleft lip and cleft palate patients and control groups were compared using Chi-square test. In the NSCL/P, the genotype in the order from highest to lowest frequency was TC (48%), followed by CC (32%) and TT (20%). Although the genotype frequency of the case and the control groups were found to be in agreement with Hardy Weinberg Equilibrium, the genotype frequencies TC, CC and TT of the polymorphism (rs11071720) among the two groups were not statistically significant which was evident from the p-value 0.8472. No significant association was found between TPM1 gene (rs11071720) polymorphism and NSCL/P.
subject: Original Clinical Research Articles
  topic: section
subject: Polymorphism; TPM1 gene; Non-syndromic cleft lip and cleft palate; Genetic disorder.
  topic: keywords
creator: Dhakshinya Murugesan
creator: A. Sumathi Felicita
creator: Vijayashree Priyadharshini Jayaseelan
rights: Copyright (c) 2024 Dhakshinya Murugesan, A. Sumathi Felicita, Vijayashree Priyadharshini Jayaseelan https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-22
publication date: 2026-04-22
starting page: 99
ending page: 109
doi: 10.15517/ijds.2024.59889

Intraoral and Extraoral Scanning Technologies in the Digital Workflow Era: An Integrative Review with Artificial Intelligence
type: item
description: The aim of this integrative review is to investigate the possibility of aligning three-dimensional intraoral scanner data with facial mobile device data, as well as comparing the effectiveness of AI-based search with manual search methods. This investigation adhered to the PRISMA guidelines aiming to answer the PICO question: “Does the facial and intraoral three-dimensional technologies are compatible and clinically applicable in oral rehabilitation?”. Was employed a search strategy incorporating specific keywords ("dental", "intraoral", "photogrammetry", "stereo photo", "scanner", "three-dimensional", "stereophotogrammetry", "scan", "virtual articulators", "facebow", "face", "facial") within multiple databases (Pubmed, BVS, and Scielo), including artificial intelligence (Scite.ai). Of the 7128 initially identified articles, 4 articles of manual search were included but none article of the artificial intelligence website were added. Among the most used: at the intraoral scanners were the TRIOS (3shape) (n=2) and for facial images the Apple Inc. cell phones (n=2). The most frequently reported software was Bellus3D (Bellus3D Inc.) with particular emphasis on the georeferencing tactic software. Several commonalities were observed, including the requirement for a 30cm spacing during cell phone-based extraoral scanning, the necessity for multiple captures, and the inclusion of landmarks and/or perioral and nasal scans. Manual searching is still the gold standard scientific searching data; Both stereophotogrammetry and mobile device scan can be used for facial scanning and the files can be integrated by utilizing georeferencing tactic software.
subject: Literature Review Articles
  topic: section
subject: Three-dimensional imaging; Artificial intelligence; Dental articulator; Temporomandibular joint; Photogrammetry.
  topic: keywords
creator: Juliana Lujan Brunetto
creator: Manuel Martin Adriazola Ique
creator: Clovis Lamartine de Moraes Melo Neto
creator: Victor Perinazzo Sachi
creator: Daniela Micheline dos Santos
creator: Marcelo Coelho Goiato
rights: Copyright (c) 2024 Juliana Lujan Brunetto, Manuel Martin Adriazola Ique, Clovis Lamartine de Moraes Melo Neto, Victor Perinazzo Sachi, Daniela Micheline dos Santos, Marcelo Coelho Goiato https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-22
publication date: 2026-04-22
starting page: 34
ending page: 42
doi: 10.15517/ijds.2024.60663

Effect of the COVID-19 Pandemic on the Educational Indicators in the Dentistry Career of the University of Costa Rica
type: item
description: This study aimed to determine the effect of the COVID-19 pandemic on the educational indicators of students who enrolled in the dentistry program at the University of Costa Rica between 2015 and 2021. Records of 522 students were analyzed, considering variables such as gender, age at entry, nationality, marital status, children, place and type of high school attended, and course performance. Information was extracted from the Student Applications System, physical records, and the Civil Registry of Costa Rica. Descriptive and bivariate analyses were performed to identify patterns and correlations between variables, and approval rates before and during the pandemic were evaluated. Seventy percent of the students were women, predominantly Costa Rican, aged between 19 and 23, from public high schools, and originating from the Greater Metropolitan Area. Terminal efficiency was zero due to the closure of clinical courses in 2020, which prevented the 2015 to 2017 cohorts from graduating within 12 semesters. The dropout rate was highest in the first and second semesters, with a progressive decrease in subsequent semesters. Most cohorts experienced delays, particularly in semesters 7-8 and 9-10. First-attempt approval rates increased in some service courses with virtualization during the pandemic, such as Intensive General Chemistry and Elementary Mathematics, but no difference was observed in the courses specific to the School of Dentistry. The COVID-19 pandemic had varying impacts on educational indicators, with virtualization improving performance in some theoretical courses while posing challenges in those with practical and clinical components.
subject: Original Clinical Research Articles
  topic: section
subject: COVID-19; Academic performance; Dentistry; Dental student; Virtual systems; Educational measurement.
  topic: keywords
creator: Natalia Gutiérrez-Marín
creator: Adrián Gómez-Fernández
creator: Cristina Castro-Sancho
rights: Copyright (c) 2024 Natalia Gutiérrez-Marín, Adrián Gómez-Fernández, Cristina Castro-Sancho https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-22
publication date: 2026-04-22
starting page: 143
ending page: 169
doi: 10.15517/ijds.2024.63048

Factors Associated with the Perception of Prehospital Internship Training of Dental and Other Health Sciences Students in the COVID-19 Context
type: item
description: During the COVID-19 pandemic, pre-internship training of Health Sciences students took on an essential role. The shift to virtual practices and a project-based learning approach brought challenges, but also opened doors for adaptation and learning in a constantly evolving healthcare landscape. To determine the factors associated with the perception of Peruvian health sciences students during the period of isolation due to the COVID-19 pandemic regarding their training prior to hospital internship. A Cross-sectional analytical study was performed. Students from professional schools of health sciences who entered the hospital internship 2022 and students from the year prior to the internship from a Peruvian public university were evaluated. Data collection was performed with a 49-question questionnaire. Female participants were more prevalent with 384 (70.98%) students while the medical career had the highest participation with 152 respondents (28.1%) followed by the dental career with 134 (24.77%). In the adjusted logistic regression model no influence of associated factors on students' perception of their preparedness for hospital internship in the isolation period due to the COVID-19 pandemic was found. Peruvian Health Sciences students self-perceive themselves prepared for hospital internship in Comprehensive Care, Prevention, Collaboration and Self-Learning, but less so in Practical Skills, Understanding Science, Interpersonal Skills and Confidence.
subject: Original Clinical Research Articles
  topic: section
subject: COVID-19; Dental students; Medical education; Perception.
  topic: keywords
creator: Juan Alvitez
creator: Luis Huarachi
creator: Abigail Temoche
creator: Miriam Rojas
creator: Daniel Alvitez-Temoche
creator: Frank Mayta-Tovalino
rights: Copyright (c) 2024 Juan Alvitez, Luis Huarachi, Abigail Temoche, Miriam Rojas, Daniel Alvitez-Temoche, Frank Mayta-Tovalino https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-22
publication date: 2026-04-22
starting page: 121
ending page: 133
doi: 10.15517/ijds.2024.60114

Immunohistochemical and Clinicopathologic Correlation of DNA Methyltransferase 3A and (C-X-C motif) Ligand 1 in Oral Squamous Cell Carcinoma
type: item
description: DNA methyl transferase 3A (DNMT3A) is an enzyme acting by adding a new methyl group to DNA favoring DNA silencing and carcinogenesis. Cytokines were said to assist epigenetic switch and enhance the activation of methyltransferases in many cancer types. The role of chemokine (C-X-C motif) ligand 1 (CXCL1) in cancer development was proved in many reports. In this study, we suggested that CXCL1 might induce activation of DNMT3A, affecting carcinogenesis of oral squamous cell carcinoma (OSCC). Immunohistochemical (IHC) scoring was calculated and statistical correlation was performed to evaluate the expression of epithelial DNMT3A in addition to epithelial and mesenchymal CXCL1 in OSCC and normal mucosal samples. DNMT3A, epithelial, and mesenchymal CXCL1 revealed a statistically significant increase in immune scoring from normal mucosa and between different tumor grades, besides a significant relation of the expressions with tumor size, stage, and lymph node involvement. Pearson’s correlation detected a statistically significant correlation of DNMT3A with epithelial and mesenchymal CXCL1. Thus, CXCL1 overexpression may be associated with DNMT3A upregulation. DNMT3A, epithelial, and mesenchymal CXCL1 were associated with histological grades and advanced tumor characters suggesting them as reliable prognostic biomarkers in patients of OSCC.
subject: Original Clinical Research Articles
  topic: section
subject: Oral squamous cell carcinoma; DNA methyltransferase 3A; CXCL1; Immunohistochemistry; Tumor grading; Clinical characteristics.
  topic: keywords
creator: Basma Abdelrahman Ahmed
creator: Mai Hafez Mohamed
rights: Copyright (c) 2024 Basma Abdelrahman Ahmed, Mai Hafez Mohamed https://creativecommons.org/licenses/by-nc-sa/4.0/
date: 2026-04-22
publication date: 2026-04-22
starting page: 110
ending page: 120
doi: 10.15517/ijds.2024.60003

Immunoexpression of ALDH1A1, FGFR2, CD44 and Caspase-3 in Oral Squamous Cell Carcinoma and Leukoplakia: A Pilot Study
type: item
description: Current research highlighted the importance to recognize feasible biomarkers for early diagnoses and treatment in oral cancer. Our study analyzed the expression and spatial distribution of ALDH1A1, FGFR2, caspase-3, and CD44 in Oral Squamous Cell Carcinoma (OSCC) and leukoplakia with and without oral mucosal dysplasia. Paraffin-embedded samples of OSCC (n=5), leukoplakia with (n=5) and without (n=5) dysplasia obtained by incisional biopsies were processed using conventional histochemical techniques. Immunohistochemistry was performed using antibodies against ALDH1A1, FGFR2, caspase-3, and CD44. Images of the immunohistochemically stained tissue sections were analyzed according to the intensity of the immunostaining of each marker and classified in Scores. The Kruskal-Wallis test was performed (p≤0.05). Our results demonstrated a statically difference in the expression of all immunomarkers between OSCC and leukoplakia without dysplasia, being more significant in FGFR2 and ALDH1A1. Within the limitations of this study, our data showed that all biomarkers were overexpressed in OSCC and leukoplakia with oral mucosa dysplasia, suggesting that the presence of dysplasia is a significant clinic-pathologic predictor for malignant transformation.
subject: Original Clinical Research Articles
  topic: section
subject: Oral cancer; Squamous cell carcinoma; Leukoplakia; ALDH1A1; FGFR2; Caspase-3; CD44.
  topic: keywords
creator: Yadira V. Boza Oreamuno
creator: Jessie F. Reyes-Carmona
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 103
ending page: 111
doi: 10.15517/ijds.2022.50369

Open Access and Bibliometric Data: Odovtos-Int.J.Dent.Sc.
type: item
description: .
subject: Editorial
  topic: section
creator: Jessie Reyes-Carmona
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 8
ending page: 9
doi: 10.15517/ijds.2023.54931

CBCT Study of Root Apices Distance to Mandibular Canal in Peruvian Population
type: item
description: The purpose of this study was to compare the average distances from the root apices of the first molars, second molars, and second premolars to the mandibular canal according to sex in the Peruvian population using cone-beam computed tomography (CBCT). Eighty CBCT scans of Peruvian patients aged from 15-80 years were examined. After locating the mandibular canal, measurements of the vertical distances from the mandibular canal to the apices of the second premolars, as well as the first molars and second molars, were made. For the statistical analysis, Student’s t test was used for both paired and unpaired samples, with a significance level of p<0.05. On the right side, the second molar presented a mean distance of 3.99mm for males and 2.87mm for females, showing a significant difference (p<0.05). When compared bilaterally, no significant differences were found (p>0.05) between the distances from the apices of the second premolars and the first and second molars to the mandibular canal. However, for the second premolars and second molars on the left side, the values were higher, with averages of 5.52mm and 3.75mm, respectively.The mesial roots of the second molars were closer to the mandibular canal. In addition, women showed shorter distances than men.
subject: Original Clinical Research Articles
  topic: section
subject: Cone-beam computed tomography; Mandibular canal; Mandibular nerve; Mandible; Tooth; Mandibular nerve injuries.
  topic: keywords
creator: Paola Manrique
creator: Andrés Agurto
creator: María Eugenia Guerrero
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 144
ending page: 154
doi: 10.15517/ijds.2023.54120

Immunological and Bacteriological Monitoring of Periodontal Tissue in Pregnancy
type: item
description: We determine periodontal pathogens in periodontal pockets from pregnant women with periodontitis and associate it to the C reactive protein (CRP), nitrates, immunoglobulin A and G (Ig A and G), and myeloperoxidase (MPO) levels in saliva to identify some biomarkers as tools to predict the periodontal status from pregnant. The samples were obtained from periodontal pockets and saliva from 100 pregnant women (PW) and 50 non-pregnant women (NPW). Every patient was evaluated by: 1) probing depth (PD) and loss of clinical attachment level (CAL); 2) in saliva; CRP, MPO, Ig A and G) and nitrite concentrations, 3) in periodontal pockets: P.gingivalis, T.forsythia, T.denticola, P.intermedia, A.actinomycetemcomitans. InfoStat/P 2008 software was used with a p-value <0.05. Clinical parameters showed stages I and II of PD in both groups. P.intermedia and A.actinomycetemcomitans were observed only in periodontal pockets from PW. The CAL was higher in pregnant of the 3rd trimester than in the other stages and was associated with low levels of IgA and the presence of P.intermedia and T. forsythia in the same trimester. The levels of IgA in saliva would reflect the immunological situation in pregnant women. This could be used to monitor the immune status of the gingival tissues during pregnancy.
subject: Original Clinical Research Articles
  topic: section
subject: Periodontitis; Porphyromonas gingivalis; IgA; Pregnant women.
  topic: keywords
creator: Natalia Solari
creator: Leonardo Salas
creator: Sandra Tabares
creator: Carolina Rosella
creator: María Matilde Usin
creator: Adela Sembaj
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 133
ending page: 143
doi: 10.15517/ijds.2023.54127

Assessment of Electromyography in Evaluating Masseter Muscle Activity in Oral Submucous Fibrosis with Different Treatment Modalities: a Systematic Review
type: item
description: Electromyography (EMG) is used for the measurement of muscle activity to characterize the nature of muscle contraction in Oral submucous fibrosis (OSMF). Aim: To assess the efficacy of EMG in evaluating masseter muscle activity in the management of OSMF. This review identified 73 records from standard databases which were rigorously screened with eligibility criteria and 3 clinical studies were identified based on our inclusion criteria. The quality of included studies was assessed by the PEDro scale and data was synthesized with detailed characterization. The Risk of Bias assessment among studies was done using the ROBINS-I tool and a meta-analysis could not be done due to high clinical heterogeneity. Our result recommends that EMG be used as an objective prognosis assessment tool by quantifying the management of OSMF irrespective of the intervention applied. However, it is not to be considered the gold standard as of now with limited data pooled and needs to be further assessed with clinical trials. EMG can be advocated as a reliable adjunct assessment for measuring the interventional outcome of OSMF irrespective of treatment modalities.
subject: Literature Review Articles
  topic: section
subject: Oral submucous fibrosis; Electromyography; Masseter muscle.
  topic: keywords
creator: Poornachitra P.
creator: Uma Maheswari T.N.
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 10
ending page: 19
doi: 10.15517/ijds.2023.54119

3D Printing Characteristics and Mechanical Properties of a Bio Scaffold Obtained from a Micro-CT Scan, Using the Fused Deposition Modeling Technique
type: item
description: The objective is to determine which biopolymer has the best 3D printing characteristics and mechanical properties for the manufacture of a bioscaffold, using the fused deposition printing technique, with models generated from an STL file obtained from a Micro-CT scan taken from a bovine iliac crest bone structure. Through an experimental exploratory study, three study groups of the analyzed biopolymers were carried out with thirteen printed structures of each one. The first is made of 100% PLA. The second, 90B, we added 1g of diatom extract, and the third, 88C, differs from the previous one in that it also contains 1g of calcium phosphate. The 39 printed structures underwent a visual inspection test, which required the fabrication of a gold standard scaffold in resin, with greater detail and similarity to the scanned bone structure. Finally, the structures were subjected to a compressive force (N) to obtain the modulus of elasticity (MPa) and compressive strength (MPa) of each one of them. A statistically significant difference (p=0.001) was obtained in the printing properties of the biomaterial 88C, compared to 90B and pure PLA and the 88C presented the best 3D printing characteristics. In addition, it also presented the best mechanical properties compared to the other groups of materials. Although the difference between these was not statistically significant (p=0.388), in the structures of the 88C biomaterial, values of compressive strength (8,84692 MPa) and modulus of elasticity (43,23615 MPa) were similar to those of cancellous bone in the jaws could be observed. Because of this result, the 88C biomaterial has the potential to be used in the manufacture of bioscaffolds in tissue engineering.
subject: Original Clinical Research Articles
  topic: section
subject: Bio scaffolding; PLA; 3D printing; FDM; Biomaterial; Bone [AND] defect; Diatoms; Calcium phosphate.
  topic: keywords
creator: Natalia González-Sánchez
creator: Nicole Jensen-Líos
creator: Diana Hernández-Montoya
creator: José Esteban Campos Zumbado
creator: Jorge Oviedo-Quirós
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 112
ending page: 122
doi: 10.15517/ijds.2022.52671

Effects of Whitening Dentifrices on the Enamel Color, Surface Roughness, and Morphology
type: item
description: The aim of this study was to evaluate the whitening and abrasion effects of dentifrices containing different whitening agents on artificially stained and unstained enamel. 160 human dental enamel discs were distributed into four groups according to the type of dentifrices applied on them (n=40): Group I, non-whitening dentifrice (control group); Group II, dentifrice containing charcoal; Group III, dentifrice containing blue covarine; Group IV, dentifrice containing hydrogen peroxide. Half of the specimens in each group were immersed in coffee solution. Color measurements were evaluated from stained and unstained specimens before and after brushing by a spectrophotometer. The surface roughness of each unstained specimen was analyzed using a profilometer after the brushing and bleaching. The surface of one randomly selected specimen from each group was observed using a scanning electron microscope (SEM). Statistical analysis of the color change was performed using the Kruskal-Wallis test. The one-way ANOVA was used to evaluate surface roughness. Group III provided significantly higher recovery on ∆E00 values than other groups on the unstained enamel (p<0.05). Group IV showed significantly the highest ∆E00 values on stained enamel (p<0.05) and also Group IV showed the highest surface roughness values (p<0.05), SEM revealed a more irregular surface in groups III and IV. It can be stated that dentifrice containing blue covarine is both an effective and a safe way to provide whiter teeth with routine home tooth brushing.
subject: Original Basic Research Articles
  topic: section
subject: Whitening dentifrices; Surface roughness; Scanning electron microscope; Tooth whitening; Tooth discoloration.
  topic: keywords
creator: Ahmet Hazar
creator: Ecehan Hazar
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 20
ending page: 29
doi: 10.15517/ijds.2022.50981

Effect of Dental Distance from Implant and MAR Algorithm on the Detection of Vertical Root Fracture in CBCT Images
type: item
description: Three-dimensional cone-beam computed tomography (CBCT) has an important role in the detection of vertical root fractures (VRFs). The effect of artifact generation by high-density objects like dental implants on image quality was well documented. This study aimed to assess the effect of tooth-implant distance and the application of metal artifact reduction (MAR) algorithm on the detection of VRFs on CBCT scans. This study was conducted on 20 endodontically treated single-rooted teeth. VRFs were induced in 10 teeth, while the other 10 remained intact. The implant was inserted in the right second premolar socket area, and two teeth were inserted in right canine and right first premolar sockets area randomly and underwent CBCT with and without the application of MAR algorithm. SPSS 21 was used to analyze the results (alpha=0.05). According to the findings of this study, all four variables of sensitivity, specificity, accuracy, and positive predictive values in diagnosis were higher in cases without MAR software at both close(roots in first premolar sockets) and far distances (roots in canine sockets) from the implant. However, the highest rate of diagnosis accuracy of the first and second radiologists was in the far distance group from the implant without MAR, and the lowest rate of diagnosis accuracy in the first and second radiologists was in the close distance to the implant. Applying MAR algorithm had no positive effect on detection of VRFs on CBCT scans in both close and distant scenarios.
subject: Original Basic Research Articles
  topic: section
subject: Metal artifact reduction algorithm; Vertical root fracture; Cone-Beam computed tomography.
  topic: keywords
creator: Fatemeh Salemi
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 65
ending page: 77
doi: 10.15517/ijds.2023.53751

The Effect of Whitening Toothpastes on Colour Change and Surface Roughness of Restorative Materials
type: item
description: To examine the colour change and surface roughness of giomer, microhybrid composite and nanohybrid composite after brushing with whitening toothpastes. Disc-shaped samples of giomer, microhybrid composite and nanohybrid composite were divided into three subgroups(n=10), with the initial colour measured with a spectrophotometer and the surface roughness measured with a mechanical profilometer. The samples, which were immersed in coffee solution were brushed once a day with whitening toothpastes (Opalescence Cool Mint (OCM), Colgate Optic White Extra Power (COW) and Signal White Now Gold (SWN)) for 12 days. Colour change and surface roughness were measured again after the colouring-brushing cycle. All of the analyses were performed using appropriate statistical hypothesis tests. The highest increase in surface roughness was seen in the microhybrid composite group applied with SWN (p<0.05). The group with the least increase was the giomer group applied with SWN (p<0.05). While the least colour change was observed in the COW applied nanohybrid composite group (∆E00=1,814), the most colour change occurred in the COW applied giomer group (∆E00=5.943). After the use of whitening toothpastes, the roughness of giomer, microhybrid composite and nanohybrid composite surfaces was increased and a colour change above the clinically accepted value was observed.
subject: Original Basic Research Articles
  topic: section
subject: Toothpastes; Colour; Composite resins.
  topic: keywords
creator: Burak Dayi
creator: Fikri Öcal
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 40
ending page: 52
doi: 10.15517/ijds.2022.52728

Elimination of E. faecalis and C. albicans Biofilm: A Comparison Between Single and Multiple File Systems in an Ex Vivo Study
type: item
description: To evaluate whether the WaveOne Gold and Reciproc single file instrumentation systems, are effective in reducing the microbial load of a mixed biofilm and the cleaning of apical third compared to the Twisted File Adaptive system (multiple-file system). Seventy mesial roots of the first and second molars were included and randomly divided into three experimental groups (n=20, n=10 controls). Biofilms were formed inside canals over 31 days. After instrumentation with the unique file systems, WaveOne Gold and Reciproc and the multiple file system Twisted File Adaptive, using 2.25% sodium hypochlorite as an irrigant in all cases, a count of colony forming units was performed using serial dilutions, cleaning of the apical third was evaluated using scanning electron microscopy. Comparisons amongst groups were made by using parametric and non-parametric statistics, according to a normal or non-normal data distribution, respectively. No significant differences in the reduction of the microbial load after employing a single-file system in comparison to the multiple-file system were found; in addition, the cleaning of the apical third was similar for the three different instrumentation systems. The single-file system is equal in effectiveness compared with the multiple-file system in reducing the microbial load.
subject: Original Basic Research Articles
  topic: section
subject: Candida albicans; Enterococcus faecalis; Reciproc; TFA; WaveOne Gold.
  topic: keywords
creator: Verónica Méndez-González
creator: Claudia Casillas-Contreras
creator: Marlen Vitales-Noyola
creator: Diana Lorena Alvarado-Hernández
creator: Ana María González-Amaro
creator: Antonio Aragón-Piña
creator: Amaury Pozos-Guillén
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 311
ending page: 322
doi: 10.15517/jbte0211

Effect of Different Obturation Techniques on Sealer Penetration into Dentinal Tubules after Final Irrigation with XP-Endo Finisher File
type: item
description: The first objective of this research was to evaluate the effectiveness of XP-Endo Finisher on dentinal tubule penetration of irrigation solution using confocal laser scanning microscopy. The main purpose of this research was to compare the effect of cold lateral condensation, continuous wave obturation and core-carrier based techniques on sealer penetration. Sixty mandibular premolars were prepared and allocated into two experimental groups (n=30) as the final irrigation technique and obturation technique experiment. In the final irrigation technique experiment, final irrigation was performed with XP-Endo Finisher, passive ultrasonic irrigation (PUI) and conventional needle irrigation (CNI) (n=10). The roots in the obturation technique experiment were also assigned into 3 groups and obturated with cold lateral condensation, continuous-wave obturation and core-carrier techniques (n=10). The most effective activation method, which emerged as a result of the first part of this study, was used as the final irrigation method in the obturation technique experiment. Then, all roots were sectioned in 1-mm-thick slices at 3mm from the apex for scanning. In terms of depth and percentage of material penetration, CNI exhibited significantly the lowest values and no significant difference was found between others. Also, there was no significant difference among obturation methods. In conclusion, XP-Endo Finisher and PUI are more effective than CNI on irrigant penetration. Sealer penetration into dentinal tubules is independent of obturation techniques.
subject: Original Basic Research Articles
  topic: section
subject: Confocal laser scanning microscopy; Dentinal tubule penetration; XP-Endo Finisher; Warm obturation techniques.
  topic: keywords
creator: Erhan Demir
creator: Selin Göker Kamalı
creator: Dilek Türkaydın
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 30
ending page: 39
doi: 10.15517/ijds.2022.51699

Autophagic-Related Anticancer Effect of Grapes Extract and Tomatoes Extract: Ex-Vivo Study
type: item
description: Cells undergo autophagy to save themselves from injury, but progressive autophagy can cause cell death. This study characterized and compared the effect of grape (resveratrol) and tomato (lycopene) extracts and their combination on modulating autophagy-related miRNA and its target gene in squamous cell carcinoma cell line. Docking analysis for extracts and selected genes was performed. Methyl Thiazol Tetrazolium assays were used to assess the cytotoxicity of extracts and their combination toward HEp-2 cells. qRT-PCR was used to quantify changes in gene expression. Data were statistically analyzed. miRNA-20a was identified as a potential effector in laryngeal cancer, and sequestosome-1 (SQSTM1) was its target gene. Docking analysis showed that resveratrol interacted with miRNA-20a and showed less affinity toward SQSTM1. Hydrogen bonds and hydrophobic interactions were predicted. In contrast, lycopene showed less affinity toward miRNA-20a than resveratrol. Increasing doses of resveratrol, lycopene, and their combination induced a statistically significant reduction in mean percent viability and mean fold changes of miRNA-20a and SQSTM1 expression in treated HEp-2 cells. Pearson’s correlation showed a statistically significant positive correlation between miRNA-20a and SQSTM1 (R=0.812, p≤0.001). Grape and tomato extracts and their combination display promising cytotoxicity against HEp-2 cells in a dose- and time-dependent fashion. Both extracts reduce the expression of miRNA-20a and SQSTM1 with subsequent inhibition autophagy and promotion of apoptosis in HEp-2 cells.
subject: Original Basic Research Articles
  topic: section
subject: HEp-2; Resveratrol; Lycopene; miRNA-20a; SQSTM1.
  topic: keywords
creator: Marwa M. Elshafei
creator: Iman M. Helmy
creator: Marwa M. Sayed
creator: Doaa B. Farag
creator: Ismail M. Shebl
creator: Shaimaa E. Ghazy
creator: Nermeen S. Afifi
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 78
ending page: 92
doi: 10.15517/ijds.2023.53752

Effect of Voxel Size of Micro-CT on the Assessment of Root Canal Preparation
type: item
description: The aim of this study was to assess the influence of micro-computed tomography (micro-CT) voxel size on evaluation of root canal preparation using rotary heat-treated nickel-titanium files. Curved mesial root canals of mandibular molars were prepared using ProDesign Logic 30/.05 (PDL) or HyFlex EDM 25/.08 (HEDM) (n=12). The specimens were scanned using micro-CT with 5μm of voxel size before and after root canal preparation. Images with sub-resolution of 10 and 20μm voxel sizes were obtained. The percentage of volume increase, debris and uninstrumented root canal surface were analyzed in the different voxel sizes. Data were compared using unpaired Student’s t-test and ANOVA statistical tests (α=0.05). No differences were observed for percentage of volume increase, debris and instrumented surface between the root canals prepared by PDL and HEDM (p>0.05). Both systems promoted higher percentage of debris in the apical third compared to the middle third (p<0.05). After instrumentation using PDL the percentage of uninstrumented surface was highr in the apical third than middle third only when analysis were performed at 5µm (p<0.05). When comparing the different voxel sizes (5,10 or 20µm), both groups showed different means for the variables, with no significant difference (p>0.05). PDL and HEDM had similar root canal preparation capacity. Micro-CT images using different voxel sizes did not influence the results of volume increase and debris evaluation. However, images at 5µm showed greater accuracy to evaluate the percentage of uninstrumented surfaces.
subject: Original Basic Research Articles
  topic: section
subject: Endodontics; Dentin; Root canal; Root canal preparation; Dental pulp cavity; X-ray microtomography.
  topic: keywords
creator: Jader Camilo Pinto
creator: Everton Lucas-Oliveira
creator: Tito Jose Bonagamba
creator: Juliane Maria Guerreiro-Tanomaru
creator: Mario Tanomaru-Filho
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 93
ending page: 102
doi: 10.15517/ijds.2023.53811

Methylation Analysis of Rb, P16, MGMT, and hMLH-1in Mucoepidermoid Carcinomas. A Pilot Study
type: item
description: Mucoepidermoid carcinoma (MC) is the most common malignant epithelial neoplasm in the salivary glands. This neoplasm has varying proportions of mucous, epidermoid, intermediate, columnar, and clear cells. MCs have been associated with CRTC1-MAML2 genes; however, their pathogenesis is uncertain. Recently, epigenetic changes have been considered a possible aetiologic factor. To identify the methylation state of RB, P16, MGMT, and hMLH genes in the three severity grades of MC were used five MCs and one healthy minor salivary gland as a control group (CG) obtained from the Pathology and Oral Medicine Laboratory and analyzed using MS-PCR to compare the presence or absence of methylation in promotor regions. The Kruskal-Wallis test was performed, with p≤0.05 considered significant. CG was employed as the normalizer of methylation levels. All assays were performed in triplicate. The mean age of our population was 52.6±18.6 years old; the total population was female and included 2 low grade, 2 intermediate grade, and 1 high grade levels of severity. When comparing the methylation status of the three histopathological grades of MC against the control, statistically significant differences were observed in Rb-M, MGMT-M, and hMLH-1-NM for high-grade severity, with p values of 0.03, 0.05, and 0.04, respectively. Methylation is a possible mechanism for pathogenesis processing of high-grade MC. However, a larger sample population is necessary to validate this finding.
subject: Original Clinical Research Articles
  topic: section
subject: Methylation; Mucoepidermoid carcinoma; RB; MGMT; hMLH-1.
  topic: keywords
creator: Luis A. Martínez-Marcial
creator: Luis F. Jacinto-Alemán
creator: David A. Trejo-Remigio
creator: Carla M. Ramírez-Martínez
creator: Elba R. Leyva-Huerta
rights: Copyright (c) 2022 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-05
publication date: 2026-05-05
starting page: 286
ending page: 295
doi: 10.15517/1hf9vs72

CD44+ Cells Influence Oral Squamous Cell Carcinomas in Two Comparative Age Groups
type: item
description: Head and neck cancer (HNC) is the sixth most common malignancy worldwide, with high morbidity and mortality rates mainly due to delayed diagnosis. Cancer stem cells (CSCs) are involved in HNC progression and treatment response, carrying important therapeutic and prognostic implications. CD44, a transmembrane glycoprotein linked to cartilage, has been proposed as a CSC biomarker and is associated with cancer progression and poor survival. CSCs may also play a role in oral carcinogenesis among young individuals. This retrospective cross-sectional study aimed to identify CD44+ cells in oral squamous cell carcinoma (OSCC) across two age groups. Thirty-six OSCC cases from a teaching service for oral histopathological diagnosis were identified between January 2005 and December 2019. Cases were divided into two groups: young group (17 patients aged ≤ 40 years) and adult/elderly group (19 patients aged ≥ 41 years). Histological slides were obtained and stained using the hematoxylin and eosin technique and the immunohistochemical technique with anti-CD44 antibodies. In the young group, males predominated (70%) with the gingiva as the main site (9 cases), while the adult/elderly group had more females (52.5%), with eight cases on the tongue. Both groups primarily showed well-differentiated OSCC. In both groups, islands of CD44+ cells, characterized by large, basophilic nuclei and scant cytoplasm, were identified in the stroma. No significant association was found between CD44 immunoreactivity and age, sex, location, or differentiation degree (P > 0.05). The identification of CD44+ could contribute to improving the diagnosis and prognosis of oral cancer, and eventually offer targeted therapies.
subject: Clinical Case Reports
  topic: section
subject: Cancer stem cells; CD44+ cells; Oral cancer; Oral squamous cell carcinoma; Invasive tumor front.
  topic: keywords
creator: Francisco G. Villanueva-Sánchez
creator: Patricia González-Alva
creator: Diana I. Rivera-Reza
creator: Luis A. Gaitán-Cepeda
rights: Copyright (c) 2026 Francisco G. Villanueva-Sánchez, Patricia González-Alva, Diana I. Rivera-Reza, Luis A. Gaitán-Cepeda. https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-04-29
publication date: 2026-04-29
starting page: 29
ending page: 42
doi: 10.15517/y02p6708

Chronic Bi-Maxillary Osteomyelitis Caused by Actinomycetes in a Patient with Severe COVID-19
type: item
description: Osteomyelitis is defined as the inflammation of the either medullary, cortical, or cancellous bone, including nerves and blood vessels, causing necrosis and bone sequestrum formation; this condition has become a rare pathology, and odontogenic infections are considered the most frequent causal factor. This case shows a patient with bi-maxillary osteomyelitis caused by Actinomyces spp, which was worsened for severe COVID-19 infection. Patient was submitted at surgery as, amplified total bilateral maxillectomy through the surgical technique Weber-Fergusson, and prolonged use of combination of antibiotics, achieved a good recovery. Two years later follow-up, the patient no show imaging or clinical evidence of the infection of osteomyelitis. The present case shows an interesting relationship between a rare infection and its association with COVID-19.
subject: Clinical Case Reports
  topic: section
subject: Actinomyces; Bilateral maxillectomy; COVID-19; Osteomyelitis.
  topic: keywords
creator: Emmanuel López-González
creator: Marlen Vitales-Noyola
creator: Diana Alvarado-Hernández
creator: Andreu Comas-García
creator: Abraham Muñoz-Ruiz
creator: Verónica Méndez-González
creator: Amaury Pozos-Guillén
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 10
ending page: 17
doi: 10.15517/ijds.2023.55954

Effect of Energy Level of Photobiomodulation Therapy on Bone Repair in Rats
type: item
description: The aim of this experimental study was to determine the effect of photobiomodulation therapy on bone repair in a rat tibia osteotomy model at 15 and 30 days. The sample consisted of 36 male Holtzman rats that were randomized into 6 equal groups. Groups A1 and A2: osteotomy + 1 J laser energy. Groups B1 and B2: osteotomy + 3 J laser energy. Groups C1 and C2 (controls): osteotomy only. The bone repair was analyzed by histological evaluation of osteoblasts and osteocytes both at 15 days (groups A1, B1, and C1) and at 30 days (groups A2, B2, and C2). Within the results, in all groups a greater number of osteoblasts was found at 15 days vs 30 days (p<0.05), and a greater number of osteocytes in B1 and C2 vs B2 and C1, respectively (p<0.05). When evaluating the 3 groups worked up to 15 days, more osteoblasts were found in A1 and C1 vs B1 (p<0.001); and osteocytes predominated in A1 and B1 vs C1 (p<0.001). At 30 days there was a greater quantity of osteoblasts in C2 vs A2 and B2 (p<0.05) and of osteocytes in C2 vs B2 (p<0.05). It is concluded that 1 J photobiomodulation therapy improved bone repair at 15 days; however, this improvement was not observed at 30 days because there were no differences between the irradiated groups and the control.
subject: Original Basic Research Articles
  topic: section
subject: Bone; Low level laser (light) therapy; Osteoblasts; Osteocytes; Photobiomodulation.
  topic: keywords
creator: José William Cubas-Mogollón
creator: Sergio Manuel Jiménez-Sánchez
creator: Eliberto Ruiz-Ramírez
creator: Carlos Humberto Erazo-Paredes
creator: Elías Ernesto Aguirre-Siancas
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 43
ending page: 54
doi: 10.15517/ijds.2023.54077

Dental Age Estimation by Assessing the Pulp Volume of Five Teeth in a Peruvian Population Using Cone Beam Computed Tomography Images
type: item
description: Dental age estimation is very important for individual identification in criminal and civil forensic investigations. One of the methods for age estimation is studying age related changes in pulp volume of teeth. The objective of the current study was to estimate dental age from the pulp volume of five different categories of teeth of a Peruvian sample using cone beam computed tomography (CBCT). Retrospective CBCT records of 231 patients [females (134), males (97), age: 12-60 years] were included in the study, categorized into five different age groups (12-19, 20-29, 30-39, 40-49, 50-59, 60 years and older). Dental pulp volume of five categories of teeth(upper canines, left upper central incisors, left upper first molars, lower left first premolars, first molars) were analyzed using Romexis® 5.3.3.5 software for each patient. There was a reduction in the pulp volume of upper right and left canine with age. The pulp volume was lowest in people aged 60 years and over. Linear regression analysis of the pulp volume and chronological age showed a coefficient of determination of 30%, suggesting a weak correlation. A weak correlation between dental pulp and age is derived. But, a robust large homogenous sample of teeth in future for different age groups may establish a reliable regression equation.
subject: Original Clinical Research Articles
  topic: section
subject: Forensic science; Forensic dentistry; Age determination by teeth; Cone beam computed tomography; Dental pulp; Secondary dentin.
  topic: keywords
creator: Juliana Magaly Salvatierra Gálvez
creator: Antonio Díaz-Suyo
creator: Erika Ruth Alvarado Muñoz
creator: Priyanka Kapoor
creator: Aman Chowdhry
creator: Ymelda Wendy Velezmoro Montes
creator: Aldren Godofredo Rivas Quispe
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 118
ending page: 129
doi: 10.15517/ijds.2023.54932

Impact of Oral Conditions on Quality of Life in Peruvian Preschoolers in Rural and Urban Areas
type: item
description: The objective of this study is to determine the impact of oral conditions on the quality of life related to the oral health of preschool children in a rural and urban area of Cusco. The study was descriptive and cross-sectional, from a population of 179 preschoolers aged 3 to 5 years, from two public early childhood education institutions, and their respective parents or caregivers in the department of Cusco, Peru. We worked with the entire population that met the inclusion and exclusion criteria, seventy-four preschool children were selected for each area, deciding to have the same amount of children per group based on the smallest group. A clinical odonto-stomatological examination was carried out for oral conditions (dental caries, malocclusion, and dental trauma) according to the WHO’s criteria and a survey that was used for sociodemographic characteristics. In addition, a validated Peruvian version of the ECOHIS questionnaire was used to obtain data on the impact on quality of life. All the variables of the total and individual scores of the ECOHIS domains were analyzed individually and the Kruskal-Wallis test was used to determine the association between variables. The oral conditions prevalence in preschool children in rural areas referring to dental caries was 100% (dmft index > 6), dental trauma 10.8%, and malocclusions 60.8%; for the urban area dental caries was 93.2% (dmft index > 6), dental trauma 9.5% and malocclusions 36.5%. Of the three oral conditions only the experience of dental caries was related to the OHRQOL of preschoolers in urban and rural areas.
subject: Original Clinical Research Articles
  topic: section
subject: Quality of life; Dental caries; Malocclusion; Dental trauma; Preschool; Peru.
  topic: keywords
creator: Maria Peña-Alegre
creator: Ingrid N. Porcel
creator: Manuel Antonio Mattos-Vela
creator: Ebingen Villavicencio-Caparó
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 162
ending page: 173
doi: 10.15517/ijds.2023.55835

The Association Between Sleep Quality, Fatigue and Periodontal Status: a Pilot Study
type: item
description: Reduced sleep duration, poor sleep quality and fatigue are related to reduced immunity and increased inflammatory markers. Due to its potential to influence inflammation, poor sleep quality and fatigue could be factors for periodontitis and quality of life. Ninety-three individuals with untreated periodontitis and thirty-one individuals with healthy gingiva were included in the study. The research involved a clinical examination and a questionnaire. Demographic information, information on oral health, oral hygiene habits, the Pittsburgh Sleep Quality Index, Jenkins Sleep Scale, Multidimensional Assessment of Fatigue Scale, and Oral Health Impact Profile-14 were included in the questionnaire. Patients were diagnosed based on the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. No statistically significant difference was revealed between sleep quality, fatigue, oral health related quality of life, and stage-grade of periodontitis (p<0.05). However, periodontitis group had higher Oral Health Impact Profile-14 scores (p<0.05). A statistically significantly lower sleep duration was observed in stage IV periodontitis group than the other groups (p<0.05). A statistically significant positive correlation was observed between the Pittsburgh Sleep Quality Index and the scores of the other questionnaires (p<0.05). The stage of periodontitis may impact sleep duration.
subject: Original Clinical Research Articles
  topic: section
subject: Fatigue; Gingival healthy; Oral health-related quality of life; Periodontal disease; Stage-grade periodontitis; Sleep quality.
  topic: keywords
creator: Zeynep Taştan Eroğlu
creator: Dilek Özkan Şen
creator: Fatma Uçan Yarkac
creator: Fatma Altiparmak
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 99
ending page: 117
doi: 10.15517/ijds.2023.54866

Terminal Efficiency, Lag and Dropout in Cohorts from 2007 to 2014 of Dental Students at the University of Costa Rica
type: item
description: Determine the terminal efficiency, lag and dropout in the cohorts of students who entered the dentistry career at the Faculty of Dentistry at University of Costa Rica in the lapse 2007 to 2014. Data from 736 files were collected. The variables considered were sex, admission age, nationality, marital status, children, admission note, domicile and high school. The data was collected from the Student Application System, the physical files, and the data base from the Supreme Court of Elections of Costa Rica. Descriptive statistics, bivariate and multivariate analysis were made, which were implemented from two logistic regression models. 98% of the students were Costa Rican, 68% women, 79% entered according to the admission note, 43% entered with an age of 18 years or less, 50% came from a public school, 77 % resided in the Greater Metropolitan Area and 95% were single and remained without children. The average terminal efficiency was 6%; 46% of students have graduated with lag, 16% are still enrolled and 32% dropped out. Sex, age, admission note, and motherhood are sociodemographic variables that are associated with terminal efficiency and dropout. The average terminal efficiency in the cohorts from 2007 to 2014 in the courses at the Faculty of Dentistry University of Costa Rica was very low, almost half of the students graduated with lag and about a third dropped out the studies. The grade from the admission note seems to be a predictor of students’ academic behavior, higher grade had more chances of graduating and less likely to dropout.
subject: Original Clinical Research Articles
  topic: section
subject: Dental students; Dental schools; Academic performance; Educational measurement; Achievement; Dentistry.
  topic: keywords
creator: Cristina Castro-Sancho
creator: Adrián Gómez-Fernández
creator: Romain Fantin
creator: Natalia Gutiérrez-Marín
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 130
ending page: 161
doi: 10.15517/ijds.2023.55636

Antimicrobial Efficacy of the Use of Mouthwash with Cetylpiridinium Chloride for Aerosol Producing Procedures. A Systematic Review
type: item
description: The present research aims to determine the antimicrobial efficacy of the mouthwashes based on cetylpyridinium chloride (CPC), before aerosol producing dental procedures. A data search was performed during August 2021 in five databases MEDLINE (PubMed), SCOPUS, SCIELO, Cochrane Central Register of Controlled Trials (CENTRAL) and Google Scholar. Randomized clinical trials (RCTs) were included based on the PICO question, comparing the efficacy of the mouthwashes based on cetylpyridinium chloride (CPC), versus other mouthwashes and water, before aerosol producing dental procedures, papers in English, Spanish and Portuguese were included without time limits. The risk of the included studies was evaluated with the tool RoB 2.0. Number of registration PROSPERO N° CRD42021275982. 120 papers were obtained in the preliminary search, discarding those that didn’t comply with the selection criteria, leaving only 3 studies. These papers reported the use of cetylpyridinium chloride (CPC) was effective for the reduction of bacteria during the ultrasonic prophylactic procedure. The use of CPC mouthwashes previous to the dental treatment with ultrasonic prophylaxis showed only antibacterial capacity.
subject: Literature Review Articles
  topic: section
subject: Mouthwash; Rinse; Cetylpyridinium; Aerosol; Antiseptics; Contaminated air.
  topic: keywords
creator: Jackeline Paola Arce-Toribio
creator: Heber Isac Arbildo Vega
creator: Ana Isabel López-Flores
rights: Copyright (c) 2023 CC-BY-NC-SA 4.0 https://creativecommons.org/licenses/by-nc-sa/4.0
date: 2026-05-04
publication date: 2026-05-04
starting page: 18
ending page: 31
doi: 10.15517/ijds.2023.55021