@article{Barroso Aragão_Tebaldi Queiroz_Ferreira_Vidal Costa_Fontes Pinheiro_Tavares Carrijo_Fonseca Andrade-Vieira_2017, title={Phytotoxicity and cytotoxicity of Lepidaploa rufogrisea (Asteraceae) extracts in the plant model Lactuca sativa (Asteraceae)}, volume={65}, url={https://revistas.ucr.ac.cr/index.php/rbt/article/view/25696}, DOI={10.15517/rbt.v65i2.25696}, abstractNote={<p><em>Lepidaploa rufogrisea</em><em> is a promising candidate in the search of natural herbicides, with compounds (sesquiterpene lactones-glaucolide B) which have been reported to present with phytotoxic potential against weeds. Thus, this work aimed to accomplish the phytochemical investigation of L. rufogrisea</em><em> as well as the evaluation of its </em><em>biological effects on the plant model Lactuca sativa</em><em>. To this end, different extracts (aqueous, hydroalcoholic and hexane) of L. rufogrisea</em><em> at different concentrations [0.25, 0.5, 1.0, 2.0 and 4.0 % (m/v)] were evaluated from macroscopic (percentage of germinated seeds, germination speed index and root length) and microscopic analysis (mitotic index and cell cycle alterations) in plantlets (150 per treatment) and meristematic cells (10 000 per treatment) of L. sativa</em><em> var. Cristina.</em> T<em>he extracts decreased the germination speed index and also the root growth of L. sativa</em><em> plantlets. Cell proliferation was not significantly affected by the extracts. However, some chromosome and nuclear alterations in the mitotic spindle were observed, due to the interference of allelochemicals present in L. rufogrisea</em><em>. Moreover, the plant model L. sativa</em><em> demonstrated to be efficient for this kind of studies. </em></p><em> </em>}, number={2}, journal={Revista de Biología Tropical}, author={Barroso Aragão, Francielen and Tebaldi Queiroz, Vagner and Ferreira, Adésio and Vidal Costa, Adilson and Fontes Pinheiro, Patricia and Tavares Carrijo, Tatiana and Fonseca Andrade-Vieira, Larissa}, year={2017}, month={Jun.}, pages={435–443} }