TY - JOUR AU - Barroso Aragão, Francielen AU - Tebaldi Queiroz, Vagner AU - Ferreira, Adésio AU - Vidal Costa, Adilson AU - Fontes Pinheiro, Patricia AU - Tavares Carrijo, Tatiana AU - Fonseca Andrade-Vieira, Larissa PY - 2017/06/01 Y2 - 2024/03/29 TI - Phytotoxicity and cytotoxicity of Lepidaploa rufogrisea (Asteraceae) extracts in the plant model Lactuca sativa (Asteraceae) JF - Revista de Biología Tropical JA - Rev. Biol. Trop. VL - 65 IS - 2 SE - Articles DO - 10.15517/rbt.v65i2.25696 UR - https://revistas.ucr.ac.cr/index.php/rbt/article/view/25696 SP - 435–443 AB - <p><em>Lepidaploa rufogrisea</em><em> is a promising candidate in the search of natural herbicides, with compounds (sesquiterpene lactones-glaucolide B) which have been reported to present with phytotoxic potential against weeds. Thus, this work aimed to accomplish the phytochemical investigation of L. rufogrisea</em><em> as well as the evaluation of its </em><em>biological effects on the plant model Lactuca sativa</em><em>. To this end, different extracts (aqueous, hydroalcoholic and hexane) of L. rufogrisea</em><em> at different concentrations [0.25, 0.5, 1.0, 2.0 and 4.0 % (m/v)] were evaluated from macroscopic (percentage of germinated seeds, germination speed index and root length) and microscopic analysis (mitotic index and cell cycle alterations) in plantlets (150 per treatment) and meristematic cells (10 000 per treatment) of L. sativa</em><em> var. Cristina.</em> T<em>he extracts decreased the germination speed index and also the root growth of L. sativa</em><em> plantlets. Cell proliferation was not significantly affected by the extracts. However, some chromosome and nuclear alterations in the mitotic spindle were observed, due to the interference of allelochemicals present in L. rufogrisea</em><em>. Moreover, the plant model L. sativa</em><em> demonstrated to be efficient for this kind of studies. </em></p><em> </em> ER -