Odovtos - International Journal of Dental Sciences ISSN Impreso: 1659-1046 ISSN electrónico: 2215-3411

OAI: https://revistas.ucr.ac.cr/index.php/Odontos/oai
Ex Vivo Evaluation of the Efficacy of Antibiotic Pastes Used as Intracanal Medication
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Keywords

Antibiotics
apical periodontitis
calcium hydroxide
endodontic treatment
microbiology

How to Cite

Calderón Brenes MQC, M. C., & Rodríguez Cavallini MQC, MSc, E. (2015). Ex Vivo Evaluation of the Efficacy of Antibiotic Pastes Used as Intracanal Medication. Odovtos - International Journal of Dental Sciences, (16), 125–133. https://doi.org/10.15517/ijds.v0i16.20331

Abstract

Clinical and research reports evidence cases of failed endodontic treatment complaining bacterial resistance to conventional therapeutic protocols. Thus, the use of an alternative intracanal medication covering a broader microbial spectrum in order to increase the success rate of endodontic treatment is necessary. In the present study the bacterial colonization of Enterococcus faecalis (ATCC 29212), Porphyromonas gingivalis (ATCC 33277), Actinomyces odontolyticus (ATCC 17929) and Prevotella bucae (LIBA-6229) on dentin specimens and in an ex vivo model simulating human root canal infection was demonstrated. Our study evaluated the antimicrobial effectiveness of two poliantibiotic pastes (amoxicillin with clavulanic acid-ciprofloxacin and metronidazole-amoxicillin-ciprofloxacin), and calcium hydroxide dressing. Both antibiotic intracanal dressings were equally effective for bacteria eradication, however in both research models, poliantibiotic pastes reveal higher antimicrobial effectiveness than calcium hydroxide. 

https://doi.org/10.15517/ijds.v0i16.20331
PDF (Español (España))

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