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© Odovtos - International Journal of Dental Sciences, 2015
Karol Ramirez DDS, MSc, PhD
Profesora Facultad de Odontologia Investigadora Asociada Centro de Neurosciencias Universidad de Costa Rica
How to Cite
Neuroimmunological Responses to Social Isolation
Vol 17 No 1 (2015): Odovtos - International Journal of Dental Sciences V.17, N.1 (JANUARY-APRIL)-2016
Published: Nov 29, 2015
Objective social isolation and perceived social isolation are psychosocial stressors that may impair the normal functioning of the neuroimmune system. Chronic activation of the neuro-immuno-endocrine communication and the consequent loss of homeostasis may lead to the appearance of pathologies and associated mood disorders. For example, alterations in the hypothalamic-pituitary- adrenal axis and sympathetic nervous system dynamics may account for the observed predisposition to inflammatory diseases following chronic social stress. Therefore, it is necessary to further study the underlying mechanisms in social isolation in order to prevent its deleterious effects on health. The objective of this New Perspective article is to supplement the understanding of the neuroimmunological responses to social isolation and provide a basis for future research in this topic.