Palabras clave
Biocolágeno; Regeneración ósea guiada; Hidroxiapatita; Periodontitis; Calidad de vida.
Cómo citar
Resumen
La regeneración ósea guiada (GBR) es el tratamiento de elección para mejorar el volumen óseo horizontal y vertical mediante injertos óseos. Las membranas GBR funcionan según el principio de prevenir la migración epitelial hacia el espacio del defecto. La hidroxiapatita se ha utilizado habitualmente como injerto óseo para defectos infraóseos. El estudio se realizó en el Departamento de Biomateriales del Saveetha Dental College. Se preparó un scaffold o andamio, el cual se caracterizó mediante microscopio electrónico de barrido (SEM), análisis de rayos X de dispersión de energía (EDAX), radiación infrarroja por transformada de Fourier (FTIR) y análisis confocal. El andamio desarrollado reveló propiedades propicias para la unión celular. Los análisis EDAX y FTIR mostraron el desarrollo exitoso de la membrana de colágeno-gelatina-hidroxiapatita. El cultivo celular y el análisis confocal revelaron una excelente biocompatibilidad con una capa homogénea de células viables. El andamio desarrollado es una membrana biogénica con un potencial de biomineralización relevante que puede utilizarse para aplicaciones GBR.
Citas
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