Abstract
After making reference to the cases of blastomycosis previously described in this country, a new case (third) of Lutz' disease was studies and classified as belonging to the "forma mixta" of Aguiar Pupo's. In spite of the therapeutics used the patient died.
With regard to the P. brasiliensis, the possibility was considered of its effecting endosporulation, and it was verified that vacuoles of fatty substances may, under certain conditions, resemble this process of reproduction.
A case of Lobo' s disease was also studied, the first one recorded in Costa Rica and outside the Amazanic area, stablishing the definite possibility that this blastomycosis is first distributed through the superficial lymphatic vessels and after a long evolution, through the deep lymphatic vessels.