Abstract
An electrom microscope model was used to study the effect of rat peritoneal macrophages on Toxoplasma gondii. 107 tachyzoites were inyected i.p. in 30 days-oId rats. After 1, 2, 4, 8 and 24 h peritoneal exudate was withdrawn and infected phagocytic cells were prepared for electronic microscope studies. Toxoplasma organisms inside of rat macrophages showed remarkable lesions such as vacuolization and organisms were totally Iysed inside of macrophages of more than 8 h infection rats. The results confirm at molecular level, the importance of rat macrophages in the natural adaptation of this rodent to T. gondii.References
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