Abstract
Between September 1979 and September 1981 a field study was conducted on the etiology of diarrheal disease in the area of Puriscal, Costa Rica. The presence of enteric pathogens was investigated in the stools of 267 diarrheic children and 190 healthy contrals. 80th groups belong to yearly cohorts recruited at birth as part of a longitudinal multidisciplinary study of mothers and children. Campylobacter fetus jejuni was identified as the only pathogen in the stools of 24 diarrheic children (9%) and in four healthy controls (2%), a significant difference (p< 0,05). The clinical features of the episodes were: irritability (77%), blood in stools (35%), anorexia (38,5%), and fever and vomiting (36%). Dehydration was not important among infected children (only one with 5% dehydration). AH children received oral salt solutions and only two were treated with antibiotics. Rotaviruses were the main etiologic agents (17%) and Campylobacter ranked second (10,5%). The frecuency of enterotoxigenic Enterobacteriaceae was similar in sick children and in controls (10% and 12% respectively).References
Blaser, M., & L.B. Neller. 1981. Campylobacter enteritis. New Engl. J. Med., 305: 1444-1452.
Butzler, J.P., P. Dekeyser, M. Detrain, & F. Dehaen. 1973. Related vibrio in stools. J. Ped., 82: 493-495.
Butzler, J.P., & M.B. Skirrow. 1979. Campylobacter enteritis. Clinics Gastroenterol., 8: 737-755.
Centers for Disease Control (CDC). 1979. Campylobacter enteritis in a household, Colorado. MMWR. Davis, J.S., & J. B. Penfold. 1979. Campylobacter urinary infection. Lancet, 1: 1091.
Glass, R. I., B. J. Stoll, M. L Huq, M. Blaser, & A.K.M. Kibriya. 1982. Epidemiological and clinical features of endemic Campylobacter jejuni infection in Bangladesh. J. Infect. Dis., (en prensa).
Hanson, L.A., & J. Winberg. 1972. Breast milk and defense against infection in the newborn. Arch. Dis. Child., 47: 845.
Jiménez. P., L. Mata, M.E. García, & W. Vargas. 1982. Estudio de Puriscal. VI. Transferencia de la tecnología de rehidratación oral del hospital al hogar rural. Rev. Méd. Hosp. Nal. Niños (Costa Rica), 17: 71-85.
Kaplan, R. L., & J.E. Barrett. 1981. Campylobacter. Marion Laboratories, Inc., Kansas City, Missouri: 1-9.
Mata, L. 1982. Estudio de Puriscal. I. Bases filosóficas, desarrollo y estado actual de la investigación aplicada en nutrición. Rev. Méd. Hosp. Nal. Niños (Costa Rica), 17: 1-19.
Mata, L., P. Jiménez, M. A. Allen, W. Vargas, M.E. García, J.J. Urrutia, & R.G. Wyatt. 1981. Diarrhea and Malnutrition: Breast-feeding intervention in a transitional population, p. 233-251. In T. Holme, J. Holmgren, M. H. Merson, & R. Molby (eds.). Acute Enteric Infection in Children. New Prospects for Teatratment and Prevention.
Mata, L., A. Simhon, R. Padilla, M.M. Gamboa, G. Vargas, F. Hernández, E. Mohs, C. Lizano, R.G. Wyatt, & R. H. Yolken. 1983. Diarrhea associated with rotaviruses, enterotoxigenic Esclzerichia coli, Campylobacter and other agents in Costa Rican Children. Amer. J. Trop. Med. Hyg., 32: 146-153.
Mawer, S.L., & B.A.M. Smith 1979. Campylobacter infection of premature baby. Lancet, 1: 1041.
National Center for Health Statistics (NCHS). 1978. Growth Curves for Children. Birth-18 years. U.S. DHEW Pub. No. (PHS) 78-1650, U.S. Dept. HEW, P.H.S. Hyattsville, MD, U.S.A., 74 pp.
Robinson, D.A., W. J. Edgar, G.L. Gibson, A.A. Matchett, & L. Robertson. 1979. Campylobacter enteritis associated with consumption of unpasteurized milk. Br. Med. J., 1: 1171-1173.
Simhon, A., & L. Mata. 1978. Anti-rotavirus antibody in human colostrum. Lancet, 1: 39-40.
Skirrow, M.B. 1977. Campylobacter enteritis: a new disease. Brit. Med. J., 2: 9-11.
Skirrow, M.B., & J. Benjamin. 1980. "1001" campylobacters: cultural characteristics of intestinal campylobacters from man and animals. J. Hyg. (Cambridge), 85: 427-442.
Véron, M., & R: Chatelain. 1973. Taxonomic study of the genus Campylobacter Sebald and Véron and designation of the neotype strain for the type species Campylobacter fetus (Smith and Taylor) Sebald & Véron . Int. J. Systematic Bacteriol., 23: 122-134.
Vives, M., L. Mata, B. Castro, A. Simhon, M. E. García, & P. Jiménez. 1982. Estudio de Puriscal. V. Infección entérica en niños menores de dos años. Rev. Méd. Hosp. Nal. Niños (Costa Rica), 17: 57-69.
Wright, E. P. 1979. Meningism associated with Campylobacter jejuni enteritis. Lancet, 1: 1092.
Yolken, R. H., R. G. Wyatt, & A. Z. Kapikian. 1977. ELlSA for rotavirus. Lancet, 2: 818.
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