Wakdenström macroglobulinemia: case report and update

Abstract

The Waldenström Macroglobulinemia is a rare hematologic malignancy characterized by medullar infiltration of  lymphocytes clonally related, which secrete monoclonal IgM protein. According to the World Health Organization  classification, this entity corresponds to a B-cell No Hodgkin Linfom known as lymphoplasmacytic lymphoma that occurs most often in people over 65 years and particularly in Caucasian males. It is essential to make a proper differential diagnosis between this disease and other similar entities associated with monoclonal component. The etiology is unknown but has been associated with genetic factors and family. We report a case of a patient with symptomatic Waldenström Macroglobulinemia, which present an aggressive clinical picture of retinal  bleeding  plus others typical signs caused by the disease.