Odovtos - International Journal of Dental Sciences ISSN Impreso: 1659-1046 ISSN electrónico: 2215-3411

OAI: https://revistas.ucr.ac.cr/index.php/Odontos/oai
Use of Ice Cream Containing Probiotic an Effective Way to Control Dental Caries?
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Keywords

Bifidobacterium lactis Bb-12; Lactobacillus acidophilus; Oral biofilm; Oral health; Streptococcus mutans; Oral Hygiene.
Bifidobacterium lactis Bb-12; Lactobacillus acidophilus; Biopelícula oral; Salud oral; Streptococcus mutans; Higiene buccal.

How to Cite

Henrique Sette-de-Souza, P., Amorim, R. de S., Cartaxo, R. de O., Silvério, S. I. C., Amorim de Lima, L. R. ., & Costa, M. J. F. (2025). Use of Ice Cream Containing Probiotic an Effective Way to Control Dental Caries?. Odovtos - International Journal of Dental Sciences, 58–68. https://doi.org/10.15517/ijds.2025.65258

Abstract

To perform a systematic review to assess the decrease in bacterial counts of Streptococcus mutans in patients who used ice cream enriched with probiotics. Is registered in the PROSPERO platform, by the code CRD42022371298. The databases were Scopus, Web of Science, Embase, Pubmed, Medline, and Science Direct, through a search algorithm based on the following PICO question: P-individuals systematically healthy and free of caries, I-enriched diet with probiotics, C-diet with ice cream without probiotics, O-S. mutans count after the diet, being only original articles. After the inclusion of metadata in the Rayyan platform, the text were read by two independent researchers, with inter-examiner kappa >0.9, with a final sample of 5 articles. There was a significant reduction of S. mutans, with p-values between <0.001 and <0.005 for all studies analyzed, maintaining the decrease for up to 7 days, conserving it for 90 days after the diet protocol, but in this case without statistical difference. The use of ice cream containing probiotics to reduce the bacterial count of S. mutans is promising, but the ideal strain and the exact number of days for maintenance of the diet are still unknown.

https://doi.org/10.15517/ijds.2025.65258
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References

Global oral health status report: towards universal health coverage for oral health by 2030 – World Health Organization; 2023.

Farias J.O. de, Santo J. de A do E., Amorim I.A., Rezende T.M.B. Triclosan antimicrobial activity against dental-caries-related bacteria. Braz J Oral Sci. 2022; 22: e238076.

Lemos J.A., Palmer S.R., Zeng L., Wen Z.T., Kajfasz J.K., Freires I.A., et al. The Biology of Streptococcus mutans. Microbiol Spectr. 2019; 7 (1): 10.1128/microbiolspec.GPP3-0051-2018.

Chen R., Du M., Liu C. Strategies for dispersion of cariogenic biofilms: applications and mechanisms. Front Microbiol. 2022; 13: 981203. doi:10.3389/fmicb.2022.981203.

Valdez R.M., Dos Santos V.R., Caiaffa K.S., Danelon M., Arthur R.A., Negrini T.C., et al. Comparative in vitro investigation of the cariogenic potential of bifidobacteria. Arch Oral Biol. 2016; 71: 97-103. doi:10.1016/j.archoralbio.2016.07.005

Sankarapandian V., Venmathi Maran B.A., Rajendran R.L., Jogalekar M.P., Gurunagarajan S., Krishnamoorthy R., et al. An Update on the Effectiveness of Probiotics in the Prevention and Treatment of Cancer. Life (Basel). 2022; 12 (1): 59. doi: 10.3390/life12010059

Amargianitakis M., Antoniadou M., Rahiotis C., Varzakas T. Probiotics, Prebiotics, Synbiotics and Dental Caries. New Perspectives, Suggestions, and Patient Coaching Approach for a Cavity-Free Mouth. Appl Sci. 2021; 11 (12): 5472.

Cosseau C., Devine D.A., Dullaghan E., Gardy J.L., Chikatamarla A., Gellatly S., et al. The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis. Infect Immun. 2008; 76 (9): 4163-75. doi: 10.1128/IAI.00188-08

Soukoulis C., Fisk I.D., Bohn T. Ice Cream as a Vehicle for Incorporating Health-Promoting Ingredients: Conceptualization and Overview of Quality and Storage Stability. Compr Rev Food Sci Food Saf. 2014; 13 (4): 627-655. doi:10.1111/1541-4337.12083

Ewida R.M., Hasan W.S., Elfaruk M.S., Alayouni R.R., Hammam A.R.A., Kamel D.G. Occurrence of Listeria spp. in Soft Cheese and Ice Cream: Effect of Probiotic Bifidobacterium spp. on Survival of Listeria monocytogenes in Soft Cheese. Foods. 2022; 11 (21): 3443. doi:10.3390/foods11213443

Kowalczyk M., Znamirowska-Piotrowska A., Buniowska-Olejnik M., Pawlos M. Sheep Milk Symbiotic Ice Cream: Effect of Inulin and Apple Fiber on the Survival of Five Probiotic Bacterial Strains during Simulated In Vitro Digestion Conditions. Nutrients. 2022; 14 (21): 4454. doi:10.3390/nu14214454

Page M.J., McKenzie J.E., Bossuyt P.M., Boutron I., Hoffmann T.C., Mulrow C.D., et al. The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ. 2021; 372: n71. doi: 10.1136/bmj.n71

Ouzzani M., Hammady H., Fedorowicz Z., Elmagarmid A. Rayyan-a Web and Mobile App for Systematic Reviews. Syst Rev. 2016; 5 (1): 210.

Atkins D., Best D., Briss P.A., Eccles M., Falck-Ytter Y., Flottorp S., et al. GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ. 2004; 328 (7454): 1490. doi: 10.1136/bmj.328.7454.1490

Taipale T., Pienihäkkinen K., Alanen P., Jokela J., Söderling E. Administration of Bifidobacterium animalis subsp. lactis BB-12 in early childhood: a post-trial effect on caries occurrence at four years of age. Caries Res. 2013; 47 (5): 364-372. doi:10.1159/000348424

Schwendicke F., Korte F., Dörfer C.E., Kneist S., Fawzy El-Sayed K., Paris S. Inhibition of Streptococcus mutans Growth and Biofilm Formation by Probiotics in vitro. Caries Res. 2017; 51 (2): 87-95. doi:10.1159/000452960

Nunpan S., Suwannachart C., Wayakanon K. Effect of Prebiotics-Enhanced Probiotics on the Growth of Streptococcus mutans. Int J Microbiol. 2019;2019:4623807. doi:10.1155/2019/4623807.

Scoffield J., Michalek S., Harber G., Eipers P., Morrow C., Wu H. Dietary Nitrite Drives Disease Outcomes in Oral Polymicrobial Infections. J Dent Res. 2019; 98 (9): 1020-1026. doi:10.1177/0022034519855348

Angarita-Díaz M.D.P., Arias J.C., Bedoya-Correa C., Cepeda M.J., Arboleda M.F., Chacón J.M., Leal Y. The effect of commercial functional food with probiotics on microorganisms from early carious lesions. Sci Rep. 2020 Jul 1; 10 (1): 10732. doi: 10.1038/s41598-020-67775-z

Nešković I., Maletin A., Brakoč J., Petrović B., Vujkov S., Veljović T. The role of yogurt enriched with LGG culture (Lactobacillus rhamnosus GG) in dental caries prevention. Srp Arh Celok Lek. 2022; 150 (1-2): 10-16.

Çaglar E., Kuscu O.O., Selvi Kuvvetli S., Kavaloglu Cildir S., Sandalli N., Twetman S. Short-term effect of ice-cream containing Bifidobacterium lactis Bb-12 on the number of salivary mutans streptococci and lactobacilli. Acta Odontol Scand. 2008; 66 (3): 154-158. doi:10.1080/00016350802089467

Singh R.P., Damle S.G., Chawla A. Salivary mutans streptococci and lactobacilli modulations in young children on consumption of probiotic ice-cream containing Bifidobacterium lactis Bb12 and Lactobacillus acidophilus La5. Acta Odontol Scand. 2011; 69 (6): 389-394. doi:10.3109/00016357.2011.572289

Ashwin D., Ke V., Taranath M., Ramagoni N.K., Nara A., Sarpangala M. Effect of Probiotic Containing Ice-cream on Salivary Mutans Streptococci (SMS) Levels in Children of 6-12 Years of Age: A Randomized Controlled Double Blind Study with Six-months Follow Up. J Clin Diagn Res. 2015; 9 (2): ZC06-ZC9. doi:10.7860/JCDR/2015/10942.5532

Mahantesha T., Reddy K.M., Kumar N.H., Nara A., Ashwin D., Buddiga V. Comparative Study of Probiotic Ice Cream and Probiotic Drink on Salivary Streptococcus mutans Levels in 6-12 Years Age Group Children. J Int Oral Health. 2015; 7 (9): 47-50.

Nagarajappa R., Daryani H., Sharda A.J., Asawa K., Batra M., Sanadhya S., et al. Effect of Chocobar Ice Cream Containing Bifidobacterium on Salivary Streptococcus mutans and Lactobacilli: A Randomised Controlled Trial. Oral Health Prev Dent. 2015; 13 (3): 213-218. doi: 10.3290/j.ohpd.a32673

Chinnappa A., Konde H., Konde S., Raj S., Beena J.P. Probiotics for future caries control: a short-term clinical study. Indian J Dent Res. 2013; 24 (5): 547-549. doi:10.4103/0970-9290.123363

Nadelman P., Magno M.B., Masterson D., da Cruz A.G., Maia L.C. Are dairy products containing probiotics beneficial for oral health? A systematic review and meta-analysis. Clin Oral Investig. 2018; 22 (8): 2763-2785. doi:10.1007/s00784-018-2682-9

Meurman J.H., Stamatova I. Probiotics: contributions to oral health. Oral Dis. 2007; 13 (5): 443-451. doi:10.1111/j.1601-0825.2007.01386.x

Jungersen M., Wind A., Johansen E., Christensen J.E., Stuer-Lauridsen B., Eskesen D. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12(®). Microorganisms. 2014; 2 (2): 92-110. doi:10.3390/microorganisms2020092

Gebara C., Chaves K.S., Ribeiro M.C.E., Souza F.N., Grosso C.R.F., Gigante M.L. Viability of Lactobacillus acidophilus La5 in pectin-whey protein microparticles during exposure to simulated gastrointestinal conditions. Food Res Int. 2013; 51 (2): 872-878. 51 (2): 87-95. doi:10.1159/000452960.

Bijle M.N., Ekambaram M., Lo E.C.M., Yiu C.K.Y. Synbiotics in caries prevention: A scoping review. PLoS One. 2020; 15 (8): e0237547. doi:10.1371/journal.pone.0237547

Siddaway A.P., Wood A.M., Hedges L.V. How to Do a Systematic Review: A Best Practice Guide for Conducting and Reporting Narrative Reviews, Meta-Analyses, and Meta-Syntheses. Annu Rev Psychol. 2019; 70: 747-770. doi:10.1146/annurev-psych-010418-102803

Tabasco R., García-Cayuela T., Peláez C., Requena T. Lactobacillus acidophilus La-5 increases lactacin B production when it senses live target bacteria. Int J Food Microbiol. 2009; 132(2-3): 109-116. doi:10.1016/j.ijfoodmicro.2009.04.004

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Copyright (c) 2025 Pedro Henrique Sette-de-Souza, Rebeca de Siqueira Amorim, Renata de Oliveira Cartaxo, Sara Isabel Cruz Silvério, Luiza Rayanna Amorim de Lima, Moan Jéfter Fernandes Costa.

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