Abstract
The Chronic Kidney Disease is a group of heterogeneous disorders that affect the structure and function of the kidney, which manifest themselves in different ways depending on the underlying cause and the stage of the disease. The complications are multisystemic and can compromise the life of the patient. The hyperphosphatemia in advanced CKD has been related to a high morbidity and mortality. The treatment aim is treating the underlying causes, mainly Diabetes Mellitus and Arterial Hypertension. In addition, the pharmacological and non-pharmacological objective is to reduce blood pressure in the kidneys and albuminuria. This is more important in a country like Costa Rica, where a chronic kidney disease has been described that is not related to the traditional risk factors, known as Mesoamerican Renal Disease.