Abstract
In the past few years there has been an explosion in the development of new therapeutic alternatives for immune therapy. Its main role is in oncology, however, each day they are more useful to treat autoimmune diseases. As aconsequence of this growth, every day we have to treat more patients that have been exposed to this kind of medication and, as we expect,patients that show their adverse effects. A 49 years old female with Ulcerative Colitis,treated with infliximab, presented to our hospital. Her main complain was night fever. The diagnostic work up showed pulmonary tuberculosis. This finding motivated us to make the present revision, assessing the basic concepts of immune therapy as well as their main adverse effects.