Revista Médica de la Universidad de Costa Rica ISSN electrónico: 1659-2441

OAI: https://revistas.ucr.ac.cr/index.php/medica/oai
Prevalence of DQ2 and DQ8 haplotypes in patients studied for celiac disease, referred to CIHATA between 2013-2015
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Keywords

celiac disease
haplotypes
enfermedad celiaca
haplotipos.

How to Cite

Suárez Sánchez, M. J., Solano Vargas, M., Zúñiga Montero, M., & Salazar Sánchez, L. (2015). Prevalence of DQ2 and DQ8 haplotypes in patients studied for celiac disease, referred to CIHATA between 2013-2015. Revista Médica De La Universidad De Costa Rica, 9(2), 63–67. https://doi.org/10.15517/rmu.v9i2.22015

Abstract

Celiac disease is a gluten protein intolerance that can occur in genetically predisposed people. Due to diagnosis difficulties, genetic determination of associated haplotypes of the disease had become relevant, mostly for its high negative predictive value. A retrospective study was conducted in patients studied for celiac disease, referred to CIHATA from January 2013 to June 2015. A total of 201 patients were analyzed, 70% were women, 44% presented at least one of the haplotypes associated with celiac disease, and 68% presented the DQ8 haplotype. Although these results cannot be generalized to the Costa Rican population, draw to attention the prevalence of the DQ8 haplotype over the DQ2 haplotype. Further analysis must be carried out to determine the prevalence of these haplotypes in the Costa Rican population and within people with the disease.
https://doi.org/10.15517/rmu.v9i2.22015
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