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Abstract
In the social security in Central America, Panamá, and the Dominican Republic, there is little information that indicates requirements and correct procedure that suppliers must follow to participate in the bidding processes. Among such information, the one related to the purchase of medicines in the institutional sphere is scarcer. The objective of this research was to develop a guide for dossier preparation for the supply of biological and biotechnological drugs in the social security institutions of Guatemala, El Salvador, Honduras, Costa Rica, Panama, Dominican Republic, and the Council of Health Ministers of Central America. For this, in force regulations for the institutional acquisition process of biological and biotechnological drugs of the countries of interest were compiled. Next, the legal and technical-scientific requirements (including technical prequalification) for these products´ institutional acquisition processes were categorized. Finally, a checklist that integrated each element found was drawn up. From this, it was identified that each institution manages the purchasing operations differently. Besides, it asks the bidders for technical and scientific requirements with different levels of demand and rigor.