Revista de Biología Tropical ISSN Impreso: 0034-7744 ISSN electrónico: 2215-2075

OAI: https://revistas.ucr.ac.cr/index.php/rbt/oai
An in vivo model to study the anti-malaric capacity oC plant extracts
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Keywords

malaria
plasmodium berghei
treatment
plants

How to Cite

Chinchilla, M., Guerrero, O. M., Abarca, G., Barrios, M., & Castro, O. (1998). An in vivo model to study the anti-malaric capacity oC plant extracts. Revista De Biología Tropical, 46(1), 35–39. https://doi.org/10.15517/rbt.v46i1.19350

Abstract

An in vivo model to study lhe antimalarie ctfeet 01' plant extraets is described. White mi ce (25-30g body weight) are lreated subeutaneously with 0.6ml of the diluted extraet stUlling seven days before P. ber¡:heí infeetion: trealmenl eontinlles lIntil death or for 30 days. Simultaneously 0.2ml of the extraet are applied per os stming three days befare infection. In a test 01' the model, treated and non-treated animals differed in body weight, survival time, haematocrite, parnsitemia development, and spleen or liver weight of recent dcad 01' killed mice.
https://doi.org/10.15517/rbt.v46i1.19350
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