Propylene glycol supplementation response in multiovulated cows for embryo production
DOI:
https://doi.org/10.15517/ma.v29i3.30837Keywords:
embryos, cattle, induced ovulation, ovarian follicles, reproduction.Abstract
Multiovulation and embryo transfer is a technique used in genetic breeding programs. The synchronization-multi ovulation protocols of bovine embryo donors, as well as the embryo collection technique, have improved, however, the technique should still be maximized. This study was done with the objective of evaluating the effect of the administration of propylene glycol (PPG) in multiovulated donor cows on the production and quality of embryos. The study was conducted in Pococi, Limon, Costa Rica, from February 2011 to January 2012. Daily and oral administration of 300 mg PPG was given from one week prior to one week after the starting of the synchronization-multiovulation protocol. Embryo flushing was performed every two months and seven cows were used. Ovarian evaluations were performed using transrectal ultrasonography before and during the days of the synchronization-multiovulation treatment. The embryos were collected and classified at the age of seven days. Treatment with PPG did not affect the number and size of ovarian follicles as measured by ultrasonography. Likewise, the number of structures collected and their quality did not improve with supplementation. The results of the experiment suggest that other factors, unrelated to the effect of PPG supplementation, affect the animal response to treatments for multiovulation and embryo collection.
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References
ATSDR (Agency for Toxic Substances and Diseases Registry). 1997. Public health statement, proylene Glycol CAS#:57-55-6. ATSDR, Atlanta, GA, USA.
Bó, G.A., and R.J. Mapletoft. 2013. Evaluation and classification of bovine embryos. Anim. Reprod. 10:344-348.
Butler, S.T. 2014. Nutritional management to optimize fertility of dairy cows in pasture-based systems. Animal 8:15-26. doi:10.1017/S1751731114000834
Butler, S.T., S.H. Pelton, and W.R. Butler. 2006. Energy balance, metabolic status, and the first postpartum ovarian follicle wave in cows administered propylene glycol. J. Dairy Sci. 89:2938-2951. doi:10.3168/jds.S0022-0302(06)72566-8
Callesen, H., P. Løvendahl, A. Bak, and T. Greve. 1995. Factors affecting the developmental stage of embryos recovered on day 7 from superovulated dairy cattle. J. Anim. Sci. 73:1539-1543. doi:10.2527/1995.7361539x
Chagas, L.M., P.J. Gore, S. Meier, K.A. Macdonald, and G.A. Verkerk. 2007. Effect of monopropylene glycol on luteinizing hormone, metabolites, and postpartum anovulatory intervals in primiparous dairy cows. J. Dairy Sci. 90:1168-1175. doi:10.3168/jds.S0022-0302(07)71603-X
Chebel, R.C., D.G. Demétrio, and J. Metzger. 2008. Factors affecting success of embryo collection and transfer in large dairy herds. Theriogenology 69:98-106. doi:10.1016/j.theriogenology.2007.09.008
Christensen, J.O., R.R. Grummer, F.E. Rasmussen, and S.J. Bertics. 1997. Effect of method of delivery of propylene glycol on plasma metabolites of feed-restricted cattle. J. Dairy Sci. 80:563-568. doi:10.3168/jds.S0022-0302(97)75971-X
Chung, Y.H., C.M. Martinez, N.E. Brown, T.W. Cassidy, and G.A. Varga. 2009. Ruminal and blood responses to propylene glycol during frequent feeding. J. Dairy Sci. 92:4555-4564. doi:10.3168/jds.2009-2131
Dijkstra, J. 1994. Production and absorption of volatile fatty acids in the rumen. Livest. Prod. Sci. 39:61-69. doi:10.1016/0301-6226(94)90154-6
Ferraz, P.A., C. Burnley, J. Karanja, A. Viera-Neto, J.E.P. Santos, R.C. Chebel, and K.N. Galvão. 2016. Factors affecting the success of a large embryo transfer program in Holstein cattle in a commercial herd in the southeast region of the United States. Theriogenology 86:1834-1841. doi:10.1016/j.theriogenology.2016.05.032
Hackbart, K.S., R.W. Bender, P.D. Carvalho, L.M. Vieira, A.R. Dresch, J.N. Guenther, H. Gencoglu, A.B. Nascimento, R.D. Shaver, and M.C. Wiltbank. 2017. Effects of propylene glycol or elevated luteinizing hormone during follicle development on ovulation, fertilization, and early embryo development. Biol. Reprod. 97:550-563. doi:10.1093/biolre/iox050
Hasler, J.F. 2014. Forty years of embryo transfer in cattle: A review focusing on the journal Theriogenology, the growth of the industry in North America, and personal reminisces. Theriogenology 81:152-169. doi:10.1016/j.theriogenology.2013.09.010
Hoedemaker, M., D. Prange, H. Zerbe, J. Frank, A. Daxenberger, and H.H. Meyer. 2004. Peripartal propylene glycol supplementation and metabolism, animal health, fertility, and production in dairy cows. J. Dairy Sci. 87:2136-2145. doi:10.3168/jds.S0022-0302(04)70033-8
Jenkins, N.T., G. Peña, C. Risco, C.C. Barbosa, A. Vieira-Neto, and K.N. Galvão. 2015. Utility of inline milk fat and protein ratio to diagnose subclinical ketosis and to assign propylene glycol treatment in lactating dairy cows. Can. Vet. J. 56 850-854.
Laskowski, D., Y. Sjunnesson, P. Humblot, G. Andersson, H. Gustafsson, and R. Båge. 2016. The functional role of insulin in fertility and embryonic development—What can we learn from the bovine model? Theriogenology 86:457-464. doi:10.1016/j.theriogenology.2016.04.062
Mikkola, M., and J. Taponen. 2017. Embryo yield in dairy cattle after superovulation with Folltropin or Pluset. Theriogenology 88:84-88. doi:10.1016/j.theriogenology.2016.09.052
Moallem, U., M. Katz, H. Lehrer, L. Livshitz, and S. Yakoby. 2007. Role of peripartum dietary propylene glycol or protected fats on metabolism and early postpartum ovarian follicles. J. Dairy Sci. 90:1243-1254. doi 10.3168/jds.S0022-0302(07)71613-2
Ordóñez, O.H., C.T. Miguel, E.G. Piñeiro, N.F. Fernandez, y C.D. Manforte. 2006. El propilenglicol mejora los resultados de la transferencia de embriones. Sito Argentino de Producción Animal, ARG. http://www.produccionbovina.com.ar/informacion_tecnica/transplante_embrionario/20-propilenglicol.pdf (consultado 8 feb. 2017).
Palma, G.A. 2008. Biotecnología de la reproducción. ReproBiotec, Mar del Plata, ARG.
Perez, B.C., J.C. Balieiro, R.V. Ventura, F. Bruneli, and M.G. Peixoto. 2017. Inbreeding effects on in vitro embryo production traits in Guzerá cattle. Animal 17:1-8. doi:10.1017/S1751731117000854
Peter, A.T., L.A. Vos, and D.J. Ambrose. 2009. Postpartum anestrus in dairy cattle. Theriogenology 71:1333-1342. doi:10.1016/j.theriogenology.2008.11.012
Piantoni, P., and M.S. Allen. 2015. Evaluation of propylene glycol and glycerol infusions as treatments for ketosis in dairy cows. J. Dairy Sci. 98:5429-5439. doi:10.3168/jds.2015-9476
Santos, J.E. 2008. Impact of nutrition on dairy cattle reproduction. In: High Plains Dairy Conference, editor, Proceedings of the High Plains Dairy Conference. High Plains Dairy Conference, Amarillo, TX, USA. p. 25-36.
Santos, J.E., H.M. Rutigliano, and M.F. Sá-Filho. 2009. Risk factors for resumption of postpartum estrous cycles and embryonic survival in lactating dairy cows. Anim. Reprod. Sci. 110:207-221. doi:10.1016/j.anireprosci.2008.01.014
Sartori, R., and C.M. Barros. 2011. Reproductive cycles in Bos indicus cattle. Anim. Reprod. Sci. 124:244-250. doi:10.1016/j.anireprosci.2011.02.006
Souza, A.L., G. Galeati, A.P. Almeida, I.J. Arruda, N. Govoni, V.J. Freitas, and D. Rondina. 2008. Embryo production in superovulated goats treated with insulin before or after mating or by continuous propylene glycol supplementation. Reprod. Domest. Anim. 43:218-221. doi:10.1111/j.1439-0531.2007.00881.x
Windholz, M., S. Budavari, and M. Co. 1983. The Merck index : an encyclopedia of chemicals, drugs, and biologicals. NCBI, MD, USA. https://www.ncbi.nlm.nih.gov/nlmcatalog/8405389 (accessed 8 Feb. 2017).
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