Abstract
Red blood cell alloimmunization is the second most common immune cause of perinatal hemolytic disease. Even though nowadays it is a less frequent condition due to the advances in its prevention through the administration of anti-Rh gamma globulin, it continues to present with compromising clinical manifestations for the fetus as fetal hydrops and anemia. This paper presents the case of a previously sensitized pregnant woman with Rh isoimmunization and manifestations of severe anemia and hydrops. The case is approached with serial intrauterine transfusions, both technical aspects and perinatal results are described.
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