Ejercicio físico, sistema inmune y composición corporal en pacientes con cáncer
DOI:
https://doi.org/10.15517/hfzc2p81Palabras clave:
physical activity, cancer, immune systemResumen
El sistema inmune está estrechamente relacionado con el proceso de carcinogénesis y está demostrado responde al efecto de diferentes modalidades de ejercicio físico. Las células Natural Killer (NK), como parte del sistema inmune innato, desempeñan un papel clave en las etapas tempranas de vigilancia tumoral, así como durante el tratamiento y el riesgo de recurrencia. Sin embargo, durante el tratamiento oncológico, su función puede verse comprometida por los efectos adversos de la quimioterapia o radioterapia. Ante ello, el ejercicio físico emerge como una estrategia no farmacológica prometedora para potenciar la función inmune y mejorar parámetros de composición corporal, la cual impacta sobre las células NK; sin embargo, esta relación sigue siendo materia de estudio. En este artículo de opinión, se discute la evidencia existente en torno a la respuesta de células NK y su relación con cambios en composición corporal en pacientes que realizan ejercicio de manera regular.
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