Keywords
Pandemics
Health Surveys
Epidemiology
COVID-19 Serological Testing
Infecciones por Coronavirus
Pandemias
Encuestas de Salud
Epidemiología
Pruebas Serológicas de COVID-19
How to Cite
Abstract
Objective: To describe study protocol and initial results of research project COVID-Inconfidentes. Method: This paper described the methodological procedures adopted and the prevalence of the SARS-CoV-2 infection in the population. A household survey was conducted between October and December 2020, in two historic cities of Brazil's mining region. Anti-SARS-CoV-2 antibody was detected using the Wondfo® rapid test. The face-to-face interview consisted of administration of a questionnaire containing registration data, sociodemographic and economic variables, living habits, general health condition, mental health, sleep habits, and eating and nutrition. Results: We evaluated 1,762 residents, of which 764 (43.4 %) were in Mariana and 998 (56.6 %) in Ouro Preto. For both cities, 51.9 % of the interviewees were female, with a predominance of the age range 35 to 59 years old (47.2 %). The prevalence of the SARS-CoV-2 infection was 5.5 % in both cities, 6.2 % in Ouro Preto, and 4.7 % in Mariana (p-value > 0.05). Conclusion: The study was effective to estimate the seroprevalence of infection by the virus and its findings will enable further analyses of the health conditions of the population related to social isolation and the risk of infection with SARS-CoV-2.
References
Aramburu, R. (2018). Sorteador de Nomes. https://play.google.com/store/apps/details?id=botecodigital.info.sorteadordenomes&hl=pt_BR&gl=US
Bertolazi, A. N., Fagondes, S. C., Hoff, L. S., Dartora, E. G., Miozzo, I. C., Barba, M. E., & Barreto, S. S. M. (2011). Validation of the Brazilian Portuguese version of the Pittsburgh Sleep Quality Index. Sleep Medicine, 12(1), 70-75. https://doi.org/10.1016/j.sleep.2010.04.020
Boas, A. R. S. V., Santos, D. G., Teixeira, J. R. B., Lourenção, L. G., Santos, J. L. G., Silva, R. A. R., Carvalho, A. R. B., Sousa, A. F. L., & Sousa, A. R. (2022). Clinical and epidemiological characteristics and individual experiences of illness in men with COVID-19: mixed method study. Sao Paulo Medical Journal, 140(6), 798-805. https://doi.org/10.1590/1516-3180.2021.0747.R1.22022022
Bontempi, E. (2021). The europe second wave of COVID-19 infection and the Italy “strange” situation. Environmental Research, 193, 110476. https://doi.org/10.1016/j.envres.2020.110476
Carvalho, L. G., Nascimento, R. M. C., Chêne, S. G. B., & Nascimento, V. B. (2022). Para uma doença emergente, uma organização insurgente: experiências quilombolas de enfrentamento da pandemia de Covid-19 no Pará. Revista Terceira Margem Amazônia, 7(18), 145-160. http://dx.doi.org/10.36882/2525-4812.2022v7i18p145-160
Celer. (2020). One Step Covid-2019 Test (Imunocromatografia). https://celer.ind.br/wp-content/uploads/2020/04/Instrucao-de-Uso-One-Step-COVID-2019-Test_Rev02_informativo.pdf
Centers for Disease Control and Prevention. (2021). Information for Laboratories about Coronavirus (COVID-19). https://www.cdc.gov/coronavirus/2019-ncov/lab/faqs.html?CDC_AA_refVal=https%3A%2F%2Fwww.cdc.gov%2Fcoronavirus%2F2019-ncov%2Flab%2Flab-testing-faqs.html
Copat, C., Cristaldi, A., Fiore, M., Grasso, A., Zuccarello, P., Signorelli, S. S., Conti, G. O., & Ferrante, M. (2020). The role of air pollution (PM and NO2) in COVID-19 spread and lethality: a systematic review. Environmental Research, 191, 110129. https://doi.org/10.1016/j.envres.2020.110129
Deeks, J. J., Dinnes, J., Takwoingi, Y., Davenport, C., Spijker, R., Taylor-Phillips, S., Adriano, A., Beese, S., Dretzke, J., di Ruffano, L. F., Harris, I. M., Price, M. J., Dittrich, S., Emperador, D., Hooft, L., Leeflang, M. MG., den Bruel, A. V., & Cochrane COVID-19 Diagnostic Test Accuracy Group. (2020). Antibody tests for identification of current and past infection with SARS‐CoV‐2. Cochrane Database of Systematic Reviews, 6(6), CD013652. https://doi.org/10.1002/14651858.CD013652
Guimarães-Ximenes-Neto, F. R., Carneiro-Flor, SM, Carvalho-da-Silva RC, Alves-Dorneles, J., Ferreira-Serafim, T., Dourado-Júnior, F. W., Marques, J. P. C., Lourenção, L. G., Ximenes, M. R. G., Diogenes-dos-Santos, F., Ribeiro, M. A., Oliveira, E. N., Freitas, C. A. S. L., & Napoleão-Albuquerque, I. M. (2021). Descriptive study of the initial cases of Covid-19 in a city in the interior of Ceará, Brazil. Archivos de Medicina (Manizales), 21(2), 536-547. https://doi.org/10.30554/archmed.21.2.3989.2021
Hallal, P. C. (2020). SOS Brazil: science under attack. The Lancet, 397(10272), 373-374. https://doi.org/10.1016/S0140-6736(21)00141-0
Hallal, P. C., Hartwig, F. P., Horta, B. L., Silveira, M. F., Struchiner, C. J., Vidaletti, L. P., Neumann, N. A., Pellanda, L. C., Dellagostin, O. A., Burattini, M. N., Victora, G. D., Menezes, A. M. B., Barros, F. C., Barros, A. J. D., & Victora, C. G. (2020). SARS-CoV-2 antibody prevalence in Brazil: results from two successive nationwide serological household surveys. The Lancet Global Health, 8(11), e1390-e1398. https://doi.org/10.1016/S2214-109X(20)30387-9
Instituto Brasileiro de Geografia e Estatística. (2013). Atlas do Censo Demográfico 2010. https://biblioteca.ibge.gov.br/index.php/biblioteca-catalogo?view=detalhes&id=264529
Li, R., Pei, S., Chen, B., Song, Y., Zhang, T., Yang, W., & Shaman, J. (2020). Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2). Science, 368(6490), 489-493. https://doi.org/10.1126/science.abb3221
Liu, Y., Gayle, A. A., Wilder-Smith, A., & Rocklöv, J. (2020). The reproductive number of COVID-19 is higher compared to SARS coronavirus. Journal of Travel Medicine, 27(2), taaa021. https://doi.org/10.1093/jtm/taaa021
Mina, M. J., Parker, R., & Larremore, D. B. (2020). Rethinking Covid-19 Test Sensitivity - A Strategy for Containment. New England Journal of Medicine, 383, e120. https://doi.org/10.1056/NEJMp2025631
Ministério da Saúde. (2011). Informações de Saúde (TABNET), Demográficas e Socioeconômicas, População residente, Censo 2010. http://www2.datasus.gov.br/DATASUS/index.php?area=0206&id=6942
Ministério da Saúde. (2020). Vigitel Brasil 2019: vigilância de fatores de risco e proteção para doenças crônicas por inquérito telefônico. http://bvsms.saude.gov.br/bvs/publicacoes/vigitel_brasil_2019_vigilancia_fatores_risco.pdf
Ministerio de Ciencia e Innovacion and Ministerio de Salud. (2020). Estudio ENE-COVID19: primera ronda. Estudio nacional de seroepidemiologia de la infección por SARS-CoV-2 en Españha. Informe preliminar 13 de mayo de 2020. https://www.sanidad.gob.es/gabinetePrensa/notaPrensa/pdf/13.05130520204528614.pdf
Morais, K. V. R., Souza, P. M. A., Morais, J. R. R., Amaral, Y. A. M., Catisani, F., Oliveira, R. M., Oliveira, R. G. C., & Pisani, G. A. A. (2020). As doenças emergentes e reemergentes e seus determinantes. Brazilian Journal of health Review, 3(4), 11227-11241. https://doi.org/10.34119/bjhrv3n4-370
Moreno, A. L., Sousa, D. A., Souza, A. M. F. L. P., Manfro, G. G., Salum, G. A., Koller, S. H., Osório, F. L., & Crippa, J. A. S. (2016). Factor structure, reliability, and item parameters of the Brazilian-Portuguese version of the GAD-7 questionnaire. Temas em Psicologia, 24(1), 367-376. http://pepsic.bvsalud.org/scielo.php?pid=S1413-389X2016000100019&script=sci_abstract&tlng=en
Nota Técnica GVIMS/GGTES/ANVISA nº 04/2020 da Agência Nacional de Vigilância Sanitária. (2020). https://www.gov.br/anvisa/pt-br/centraisdeconteudo/publicacoes/servicosdesaude/notas-tecnicas/nota-tecnica-gvims_ggtes_anvisa-04_2020-25-02-para-o-site.pdf
Nota Técnica nº 5/2020-SAPS/MS do Ministério da Saúde. (2020). https://egestorab.saude.gov.br/image/?file=20200416_N_NotaTecnican5_7232065694668476750.pdf
Palma, E. M. S., Sousa, A. R., Teixeira, J. R. B., Moreira, W. C., Araújo, A. C. M., Souza, L. F. V., Anjos, J. C. R., Almeida Portela, H. S., Carvalho, H. E. F., Oliveira Muniz, V., Barreto, N. M. P. V., Almeida, É. S., Mota, T. N., Santos, S. D., Silva Souza, A. T., Silva, J. C., Almeida, C. A. P. L., Lourenção, L. G., Queiroz, A. M., … Mendes, I. A. C. (2022). Influence of Sociodemographic and Emotional Factors on the Relationship between Self-Compassion and Perceived Stress among Men Residing in Brazil during the COVID-19 Pandemic. International Journal of Environmental Research and Public Health, 19(13), 8159. https://doi.org/10.3390/ijerph19138159
Qiu, J. (2020). Covert coronavirus infections could be seeding new outbreaks. Nature, 20 March 2020. https://doi.org/10.1038/d41586-020-00822-x
Resolução no 466, de 12 de dezembro de 2012 do Ministério da Saúde. (2012). https://bvsms.saude.gov.br/bvs/saudelegis/cns/2013/res0466_12_12_2012.html
Santos, I. S., Tavares, B. F., Munhoz, T. N., Almeida, L. S. P., Silva, N. T. B., Tams, B. D., Patella, A. M., & Matijasevich, A. (2013). Sensitivity and specificity of the Patient Health Questionnaire-9 (PHQ-9) among adults from the general population. Cadernos de Saúde Pública, 29(8), 1533-1543. https://doi.org/10.1590/0102-311x00144612
Santos, V. A., Rafael, M. M., Sabino, E. C., & Duarte, A. J. S. (2020). Sensitivity of the Wondfo One Step COVID-19 test on using serum samples. Clinics, 75, e2013. http://dx.doi.org/10.6061/clinics/2020/e2013
Silveira, M. F., Barros, A. J. D., Horta, B. L., Pellanda, L. C., Victora, G. D., Dellagostin, A. O., Struchiner, C. J., Burattini, M. N., Valim, A. R. M., Berlezi, E. M., Mesa, J. M., Ikeda, M. L. R., Mesenburg, M. A., Mantesso, M., Dall’Agnol, M. M., Bittencourt, R. A., Hartwig, F. P., Menezes, A. M. B., Barros, ... Victora, C. G. (2020). Population-based surveys of antibodies against SARS-CoV-2 in Southern Brazil. Nature Medicine, 26, 1196-1199. https://doi.org/10.1038/s41591-020-0992-3
Sousa, A. R., Moreira, W. C., Santana, T. S., Araújo, I. F. M., Borges, C. C. L., Almeida, E. S., Mercês, M. C., Silva, R. A. R., Teixeira, J. R. B., Lourenção, L. G., Gomes, N. P., Carvalho, E. S., Sousa. Á. F. L., Almeida, L. C. G., Viana, L. V. M., & Pereira, Á. (2022). Sociohistorical Analysis of Normative Standards of Masculinity in the Pandemic of COVID-19: Impacts on Men’s Health/Mental Health. Frontiers in Psychology, 13, 775337. https://doi.org/10.3389/fpsyg.2022.775337
Sousa, A. R., Teixeira, J. R. B., Palma, E. M. S., Moreira, W. C., Santos, M. B., Carvalho, H. E. F., Almeida, É. S., Florencio, R. M. S., Queiroz, A. M., Merces, M. C., Mota, T. N., Araújo, I. F. M., Silva, J. C., Santos, S. D., Camargo, E. L. S., Lourenção, L. G., Silva, R. A. R., Carvalho, E. S. S., Lua, I., … Cruz Sequeira, C. A. (2021). Psychological Distress in Men during the COVID-19 Pandemic in Brazil: The Role of the Sociodemographic Variables, Uncertainty, and Social Support. International Journal of Environmental Research and Public Health, 19(1), 350. https://doi.org/10.3390/ijerph19010350
World Health Organization. (2020a). Advice on the use of point-of-care immunodiagnostic tests for COVID-19. https://www.who.int/news-room/commentaries/detail/advice-on-the-use-of-point-of-care-immunodiagnostic-tests-for-covid-19
World Health Organization. (2020b). Population-based age-stratified seroepidemiological investigation protocol for COVID-19 virus infection, 17 March 2020. https://apps.who.int/iris/handle/10665/331656
World Medical Association. (1997). Declaration of Helsinki: Recommendation guiding physicians in biomedical research involving humans subjects. JAMA, 277, 925-926.
Ying, L., Yue-ping, L., Bo, D., Feifei, R., Yue, W., Jinya, D., & Qianchuan, H. (2020). Diagnostic Indexes of a Rapid IgG/IgM Combined Antibody Test for SARS-CoV-2 [preprint]. medRxiv preprint. https://doi.org/10.1101/2020.03.26.20044883
Comments
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Copyright (c) 2023 Adriana Lúcia Meireles, Luciano Garcia Lourenção, Luiz Antônio Alves de Menezes-Júnior, Hillary Nascimento Coletro, Irene Carolina Sousa Justiniano, Samara Silva de Moura, Amanda Popolino Diniz, Thaís da Silva Sabião, Ana Maria Sampaio Rocha, Aline Priscila Batista, Nara Nunes Lage, Bárbara dos Santos Simões, Carolina Ali Santos, Raquel de Deus Mendonça, Amanda Cristina de Souza Andrade, Keila Furbino Barbosa, Cássio Zumerle Masioli , Júlia Cristina Cardoso Carraro, Mariana Carvalho de Menezes , Renata Cristina Rezende Macedo Nascimento , Leonardo Roever, Waleska Teixeira Caiaffa , George Luiz Lins Machado-Coelho